David Whitehouse, Consultant Biotechnologist and Research Fellow, London School of Hygiene and Tropical Medicine, London. Ralph Rapley, Department of Biosciences, University of Hertfordshire, Hatfield.

• List of contributors Preface1 Cytochrome P450 pharmacogenetics: from bench to bedsideImtiaz M. Shah, Catherine J. Breslin and Simon P. Mackay2 Cancer biomarkers for diagnosis, prognosis and therapyDebmalya Barh, Vaishali Agte, Dipali Dhawan, Varsha Agte and Harish Padh3 HER2 targeted therapy-induced gastrointestinal toxicity: from the clinical experience to possible molecular mechanismsNoor Al-Dasooqi, Rachel J. Gibson, Joanne M. Bowen and Dorothy M. Keefe4 Antibody-targeted photodynamic therapyMahendra Deonarain, Ioanna Stamati and Gokhan Yahioglu5 Anti-ageing strategy of the lung for chronic inflammatory respiratory disease – targeting protein deacetylasesKazuhiro Ito and Nicolas Mercado6 RNA interference: from basics to therapeuticsSunit Kumar Singh and Praveensingh B. Hajeri7 Delivery of RNAi effectors by tkRNAiHermann Lage, Andrea Kr¨uhn and Johannes H. Fruehauf8 Human stem cell therapyM. Ian Phillips, Yao-Liang Tang and Henrique Cheng9 Gene therapy in organ transplantationThomas Ritter and Matthew D. Griffin10 Advances in the treatment of Alzheimer’s diseaseMichael S. Rafii11 Novel molecular therapeutics in Parkinson’s diseaseSusana Gonc¸alves, Hugo Vicente Miranda and Tiago F. Outeiro12 Emerging insights and therapies for human microbial diseaseJoanne L. Fothergill and Craig Winstanley13 Vaccine design and vaccinationNiall McMullanIndex 305

David Whitehouse, Consultant Biotechnologist and Research Fellow, London School of Hygiene and Tropical Medicine, London. Ralph Rapley, Department of Biosciences, University of Hertfordshire, Hatfield.

• List of contributors Preface1 Cytochrome P450 pharmacogenetics: from bench to bedsideImtiaz M. Shah, Catherine J. Breslin and Simon P. Mackay2 Cancer biomarkers for diagnosis, prognosis and therapyDebmalya Barh, Vaishali Agte, Dipali Dhawan, Varsha Agte and Harish Padh3 HER2 targeted therapy-induced gastrointestinal toxicity: from the clinical experience to possible molecular mechanismsNoor Al-Dasooqi, Rachel J. Gibson, Joanne M. Bowen and Dorothy M. Keefe4 Antibody-targeted photodynamic therapyMahendra Deonarain, Ioanna Stamati and Gokhan Yahioglu5 Anti-ageing strategy of the lung for chronic inflammatory respiratory disease – targeting protein deacetylasesKazuhiro Ito and Nicolas Mercado6 RNA interference: from basics to therapeuticsSunit Kumar Singh and Praveensingh B. Hajeri7 Delivery of RNAi effectors by tkRNAiHermann Lage, Andrea Kr¨uhn and Johannes H. Fruehauf8 Human stem cell therapyM. Ian Phillips, Yao-Liang Tang and Henrique Cheng9 Gene therapy in organ transplantationThomas Ritter and Matthew D. Griffin10 Advances in the treatment of Alzheimer’s diseaseMichael S. Rafii11 Novel molecular therapeutics in Parkinson’s diseaseSusana Gonc¸alves, Hugo Vicente Miranda and Tiago F. Outeiro12 Emerging insights and therapies for human microbial diseaseJoanne L. Fothergill and Craig Winstanley13 Vaccine design and vaccinationNiall McMullanIndex 305

David Whitehouse, Consultant Biotechnologist and Research Fellow, London School of Hygiene and Tropical Medicine, London. Ralph Rapley, Department of Biosciences, University of Hertfordshire, Hatfield.

• List of contributors Preface1 Cytochrome P450 pharmacogenetics: from bench to bedsideImtiaz M. Shah, Catherine J. Breslin and Simon P. Mackay2 Cancer biomarkers for diagnosis, prognosis and therapyDebmalya Barh, Vaishali Agte, Dipali Dhawan, Varsha Agte and Harish Padh3 HER2 targeted therapy-induced gastrointestinal toxicity: from the clinical experience to possible molecular mechanismsNoor Al-Dasooqi, Rachel J. Gibson, Joanne M. Bowen and Dorothy M. Keefe4 Antibody-targeted photodynamic therapyMahendra Deonarain, Ioanna Stamati and Gokhan Yahioglu5 Anti-ageing strategy of the lung for chronic inflammatory respiratory disease – targeting protein deacetylasesKazuhiro Ito and Nicolas Mercado6 RNA interference: from basics to therapeuticsSunit Kumar Singh and Praveensingh B. Hajeri7 Delivery of RNAi effectors by tkRNAiHermann Lage, Andrea Kr¨uhn and Johannes H. Fruehauf8 Human stem cell therapyM. Ian Phillips, Yao-Liang Tang and Henrique Cheng9 Gene therapy in organ transplantationThomas Ritter and Matthew D. Griffin10 Advances in the treatment of Alzheimer’s diseaseMichael S. Rafii11 Novel molecular therapeutics in Parkinson’s diseaseSusana Gonc¸alves, Hugo Vicente Miranda and Tiago F. Outeiro12 Emerging insights and therapies for human microbial diseaseJoanne L. Fothergill and Craig Winstanley13 Vaccine design and vaccinationNiall McMullanIndex 305