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    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Biologi
    4. Biokemi

    Proteins in Solution and at Interfaces

    Methods and Applications in Biotechnology and Materials Science

    AvJuan M. Ruso,Ángel Piñeiro

    Inbunden, Engelska, 2013

    Del 8 i serien Wiley Series on Surface and Interfacial Chemistry

    1 946 kr

    Skickas . Fri frakt över 249 kr.

    Beskrivning

    Explores new applications emerging from our latest understanding of proteins in solution and at interfacesProteins in solution and at interfaces increasingly serve as the starting point for exciting new applications, from biomimetic materials to nanoparticle patterning. This book surveys the state of the science in the field, offering investigators a current understanding of the characteristics of proteins in solution and at interfaces as well as the techniques used to study these characteristics. Moreover, the authors explore many of the new and emerging applications that have resulted from the most recent studies. Topics include protein and protein aggregate structure; computational and experimental techniques to study protein structure, aggregation, and adsorption; proteins in non-standard conditions; and applications in biotechnology.Proteins in Solution and at Interfaces is divided into two parts: Part One introduces concepts as well as theoretical and experimental techniques that are used to study protein systems, including X-ray crystallography, nuclear magnetic resonance, small angle scattering, and spectroscopic methodsPart Two examines current and emerging applications, including nanomaterials, natural fibrous proteins, and biomolecular thermodynamicsThe book's twenty-three chapters have been contributed by leading experts in the field. These contributions are based on a thorough review of the latest peer-reviewed findings as well as the authors' own research experience. Chapters begin with a discussion of core concepts and then gradually build in complexity, concluding with a forecast of future developments.Readers will not only gain a current understanding of proteins in solution and at interfaces, but also will discover how theoretical and technical developments in the field can be translated into new applications in material design, genetic engineering, personalized medicine, drug delivery, biosensors, and biotechnology.

    Produktinformation

    • Utgivningsdatum:2013-04-30
    • Mått:226 x 286 x 33 mm
    • Vikt:1 424 g
    • Format:Inbunden
    • Språk:Engelska
    • Serie:Wiley Series on Surface and Interfacial Chemistry
    • Antal sidor:500
    • Förlag:John Wiley & Sons Inc
    • ISBN:9780470952511

    Utforska kategorier

    • Biokemi inom Naturvetenskap och teknik
    • Biologi inom Naturvetenskap och teknik
    • Organisk kemi inom Naturvetenskap och teknik

    Mer om författaren

    JUAN M. RUSO is currently Associate Professor in the Department of Applied Physics at the University of Santiago de Compostela, Spain. He has contributed to more than 100 publications on a broad range of physical, chemical, and biophysics studies. His research interests include protein ligand interactions, thermal stabilization of protein, Phase behavior, and self-assembly processes in soft matter systems, biocompatible materials design, and nanocarrier design for targeted drug delivery.ÁNGEL PIÑEIRO is an IPP Research Fellow at the Department of Applied Physics of the University of Santiago de Compostela, Spain. His current research interests include the design and characterization of self-assembled systems as well as the study of macromolecules in solution, embedded in membranes or at interfaces. His work is mainly based on computational methods including multiscale molecular dynamics simulations and the development of software for the analysis of different experimental properties.

    Innehållsförteckning

    • PREFACE ixCONTRIBUTORS xiiiPART I1 X-Ray Crystallography of Biological Macromolecules: Fundamentals and Applications 3Antonio L. Llamas-Saiz and Mark J. van Raaij2 Nuclear Magnetic Resonance Methods for Studying Soluble, Fibrous, and Membrane-Embedded Proteins 23Victoria A. Higman3 Small-Angle X-Ray Scattering Applied to Proteins in Solution 49Leandro Ramos Souza Barbosa, Francesco Spinozzi, Paolo Mariani, and Rosangela Itri4 Analyzing the Solution State of Protein Structure, Interactions, and Ligands by Spectroscopic Methods 73Veronica I. Dodero and Paula V. Messina5 Resolving Membrane-Bound Protein Orientation and Conformation by Neutron Reflectivity 99Hirsh Nanda6 Investigating Protein Interactions at Solid Surfaces—In Situ, Nonlabeling Techniques 113Olof Svensson, Javier Sotres, and Alejandro Barrantes7 Calorimetric Methods to Characterize the Forces Driving Macromolecular Association and Folding Processes 139Conceic¸ ˜ao A.S.A. Minetti, Peter L. Privalov, and David P. Remeta8 Virtual Ligand Screening Against Comparative Models of Proteins 179Hao Fan9 Atomistic and Coarse-Grained Molecular Dynamics Simulations of Membrane Proteins 193Thomas J. Piggot, Peter J. Bond, and Syma KhalidPART II10 Preparation of Nanomaterials Based on Peptides and Proteins 209Yujing Sun and Zhuang Li11 Natural Fibrous Proteins: Structural Analysis, Assembly, and Applications 219Mark J. van Raaij and Anna Mitraki12 Amyloid-Like Fibrils: Origin, Structure, Properties, and Potential Technological Applications 233Pablo Taboada, Silvia Barbosa, Josue Juarez, Manuel-Alatorre Meda, and Výctor Mosquera13 Proteins and Peptides in Biomimetic Polymeric Membranes 283Alfredo Gonzalez-Perez14 Study of Proteins and Peptides at Interfaces By Molecular Dynamics Simulation Techniques 291David Poger and Alan E. Mark15 A Single-Molecule Approach to Explore the Role of the Solvent Environment in Protein Folding 315Katarzyna Tych and Lorna Dougan16 Enhanced Functionality of Peroxidases By Its Immobilization at The Solid–Liquid Interface of Mesoporous Materials and Nanoparticles 335Jose Campos-Teran, Iker Inarritu, Jorge Aburto, and Eduardo Torres17 Superactivity of Enzymes in Supramolecular Hydrogels 353Ye Zhang and Bing Xu18 Surfactant Proteins and Natural Biofoams 365Malcolm W. Kennedy and Alan Cooper19 Promiscuous Enzymes 379Luis F. Olguin20 Thermodynamics and Kinetics of Mixed Protein/Surfactant Adsorption Layers at Liquid Interfaces 389Reinhard Miller, E.V. Aksenenko, V.S. Alahverdjieva, V.B. Fainerman, C.S. Kotsmar, J. Kragel, M.E. Leser, J. Maldonado-Valderrama, V. Pradines, C. Stefaniu, A. Stocco, and R. Wustneck21 Application of Force Spectroscopy Methods to the Study of Biomaterials 429Chuan Xu and Erika F. Merschrod S.22 Protein Gel Rheology 437Katie Weigandt and Danilo Pozzo23 Exploring Biomolecular Thermodynamics in Aqueous and Nonaqueous Environments using Time-Resolved Photothermal Methods 449Randy W. Larsen, Carissa M. Vetromile, William A. Maza, Khoa Pham, Jaroslava MiksovskaINDEX 473