Advances in Drug Discovery Techniques

Inbunden, Engelska, 1998

3 213 kr

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Beskrivning

This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic approaches to drug discovery. Moreover, chapters also focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. Typical screening studies and their link to robotics and informatics are also presented in detail, together with an overview of current progress within antisense therapeutics. Overall, this book will be an excellent reference source for all individuals interested in making sense of the rapid changes in drug discovery that result from developments in molecular biology, robotics and informatics.

Produktinformation

Utgivningsdatum:1998-06-08
Mått:153 x 238 x 19 mm
Vikt:454 g
Format:Inbunden
Språk:Engelska
Antal sidor:224
Förlag:John Wiley & Sons Inc
ISBN:9780471975090

Utforska kategorier

Tillverkningsindustri inom Ekonomi och Ledarskap
Medicinsk utrustning och medicinska tekniker inom Medicin
Farmakologi inom Medicin

Mer om författaren

Alan L. Harvey is the author of Advances in Drug Discovery Techniques, published by Wiley.

Innehållsförteckning

Sense, Nonsense and Antisense: Different Approaches to Drug Discovery (A. Harvey). Natural Products for Durg Discovery: An Overview (P. Waterman). Advanced Screening Technology and Informatics for Natural Products Drug Discovery (D. Hill). Discovery of Specific Tyrosine Kinase Inhibitors from Microbial and Botanical Sources (G. McMahon, et al.). Plant Cell Culture: A Vehicle for Drug Discovery (A. Stafford, et al.). Pharmacy of the Deep -Marine Organisms as Sources of Anticancer Agents (M. Jaspars). Drug Discovery by Using Molecular Biology to Reprogramme Microorganisms (I. Hunter). Small Molecule Drug Screening Based on Surface Plasmon Resonance (S. Kumar & K. Gunnarsson). An Overview of Combinatorial Chemistry and Its Applications to the Identification of Matric Metalloproteinase Inhibitors (MMPIs) (S. Shuttleworth). New Methods for Structure-based De Novo Drug Design (B. Waszkowycz). Current and Future Capabilities in Automated Drug Screening and Development (I. Norrington). Antisense Oligonucleotide Therapeutics (C. Bennett, et al.). Index.