Hans-Heinrich Limbach, Amnon Kohen

"Kohen and Limbach have produced a massive text that broadly covers the subject of isotope effects in 42 chapters written by experts in the field. Collectively, the chapters demonstrate the very close connection between experiment and theory that is the hallmark of research on isotope effects. …All of the chapters begin with a helpful table of contents, and most have introductory sections that provide excellent background for the subsequent advanced material."-W. Phillip Huskey, Journal of the American Chemical Society, 2006"Written by internationally recognized researchers from 13 countries, this volume (42 chapters) brings together a wide scope of different perspectives and practical developments and applications into a comprehensive reference of isotope effects that reflect the most current state-of-the-art." – In Anticancer Research, September/ October 2007, Vol. 27, No. 5A

• Equilibrium Isotope Effects and Isotope Separation. Condensed Matter and Hydrogen Bond Isotope Effects. Isotope Effects in Chemical Dynamics. Atmospheric, Geologic, and Extraterrestrial Studies. Isotope Effects in Organic Reactions. Kinetic Isotope Effects of Hydrogen Transfer Reactions of Polyatomic Molecules in Condensed Phases. Kinetic Isotope Effects of Hydrogen Transfer Reactions of Complex Systems. Enzyme Mechanisms from Isotope Effects. Hydrogen Bonding and Solvent Isotope Effects in Enzymes.

Hans-Heinrich Limbach, Amnon Kohen

"Kohen and Limbach have produced a massive text that broadly covers the subject of isotope effects in 42 chapters written by experts in the field. Collectively, the chapters demonstrate the very close connection between experiment and theory that is the hallmark of research on isotope effects. …All of the chapters begin with a helpful table of contents, and most have introductory sections that provide excellent background for the subsequent advanced material."-W. Phillip Huskey, Journal of the American Chemical Society, 2006"Written by internationally recognized researchers from 13 countries, this volume (42 chapters) brings together a wide scope of different perspectives and practical developments and applications into a comprehensive reference of isotope effects that reflect the most current state-of-the-art." – In Anticancer Research, September/ October 2007, Vol. 27, No. 5A

• Equilibrium Isotope Effects and Isotope Separation. Condensed Matter and Hydrogen Bond Isotope Effects. Isotope Effects in Chemical Dynamics. Atmospheric, Geologic, and Extraterrestrial Studies. Isotope Effects in Organic Reactions. Kinetic Isotope Effects of Hydrogen Transfer Reactions of Polyatomic Molecules in Condensed Phases. Kinetic Isotope Effects of Hydrogen Transfer Reactions of Complex Systems. Enzyme Mechanisms from Isotope Effects. Hydrogen Bonding and Solvent Isotope Effects in Enzymes.