Neuropsychopharmacology of the Trace Amines

Experimental and Clinical Aspects

AvAlan A. Boulton,Peter R. Bieck

Inbunden, Engelska, 1986

Del i serien Experimental and Clinical Neuroscience

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Beskrivning

A multidisciplinary survey of the progress in research on CNS trace amines. The profound pharmacological, physiological, and behavioural effects of these endogenous substances, effects whose proper understanding is rapidly emerging as a result of strong methodological advances, promises great progress in the clinical treatment of psychiatric and neurological disorders. This work should be of interest to all experimental and clinical neuroscientists.

Produktinformation

Utgivningsdatum:1986-03-15
Mått:155 x 235 x 29 mm
Vikt:916 g
Format:Inbunden
Språk:Engelska
Serie:Experimental and Clinical Neuroscience
Antal sidor:510
Upplaga:1985
Förlag:Humana Press Inc.
ISBN:9780896030992

Utforska kategorier

Psykiatri inom Medicin
Farmakologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

The Trace Amines: Recent Overview and Future Pointers.- Neuropsychopharmacology.- Invited Communications.- Cerebral 2-Phenylethylamine Concentrations and Turnover Not Influenced by Various Pharmacological Treatments in Rats.- Pharmacological Profile of Beta-Phenylethylamine on Dopaminergic and Noradrenergic Neurotransmission in Rat Cerebral Slices:Comparison with Amphetamine and Other Trace Amines.- Further Investigation of the Metabolism of Two Trace Amines, Beta- Phenylethylamine and ?-Tyramine by Rat Aorta Semicarbazide- Sensitive Amine Oxidase.- In Vivo Discriminative Stimulus (CUE) Properties in Rats of Beta- Phenylethylamine.- Effect of Psychoactive Drugs on Behavior Induced by 2- Phenylethylamine in Rats.- Potentiation of the Biochemical Effects of Beta-Phenylethylamine and Tryptamine by Deuterium Substitution.- Possible Pathways for Some Trace Amine-Containing Neurons.- [3H]Tryptamine Receptors in Rat Brain.- Tryptamine, Tyramine, and Histamine Immunoreactivities in Specific Neurones of the Gastropod CNS.- Behavioral and Pharmacological Characterisation of Tryptamine- Induced Excitation Syndrome in Rat.- Biosynthesis of Beta-Carbolines.- Brain Octopamine and Strain Differences in Avoidance Behavior. Prenatal Ontogenesis of Phenolamines.- Relations Between MPTP (1 -Methyl-4-Phenyl-l,2,3,6- Tetrahydropyridine), the Neurotoxin MPP+ (1-Methyl-4-Phenyl- Pyridinum Ion), and MRO in Rat Brain.- Free Communications.- Prodrugs of Trace Amines.- The Effect of Deuterium Labeling on Ionization Constants and Lipophilicity of Trace Amines.- Beta-Phenylethylamine and Amphetamine Compared in Tests of Anorexia and Place-Preference Conditioning.- Interaction of Trace Amines with Serotonin Recognition Sites in Rat Brain.- Effects of 2-Phenylethylamine and Tyramine on CentralNoradrenaline and Dopamine Systems: An Electrophysiological Study.- Further Investigations of the Interaction Between Phenylethylamine and Dopamine in the Rat Nigrostriatal System.- Tranylcypromine and an N-Cyanoethyl Analogue: Effects on Brain Levels of the Trace Amines Beta-Phenylethylamine and Tryptamine.- In Vivo Release of Endogenous Dopamine from Rat Caudate Nucleus by Phenylethylamine.- Phenylethylamine and 5-Hydroxytryptamine Function.- Distribution of CNS Sites Sensitive To Tryptamine and Serotonin in Pain Processing.- Tyrosine, Tyramine, and Dopamine Concentrations After Electrolytic Lesions of Midbrain Raphé Nuclei.- Pharmacological Characterisation of Octopamine-Sensitive Adenylate Cyclase in Periplaneta Americana.- Effects of Drugs on Octopamine Metabolism in the Rat.- Head-Twitch Response Induced by ?-Hydroxyamphetamine in Mice.- Catecholamine, Serotonin, and Tetrahydrobiopterin Levels in Brain Regions of Male, C57B1/6J Mice Treated with MPTP (l-Methyl-4- Phenyl-1,2,3,6-Tetrahydropyridine).- The Effects of Porgyline, Clorgyline, Deprenyl, and Their Metabolites on Rat Peripheral and Central Biogenic Amines: MAOI, A Look Behind the Label.- Direct and Indirect Effects of MAO Inhibitors and Trace Amines on Serotonergic Neurotransmission.- Some Aspects of the Oxidative Deamination of Tryptamine by MAO-R and MAO-B in Different Tissues.- Possible Interference of Uric Acid in the Measurement of Catecholamines by HPLC with Electrochemical Detection.- Clinical Pharmacology.- Invited Communications.- Chronic Administration of Monoamine Oxidase Inhibitors: Basic and Clinical Investigations.- Further Studies on Platelet Monoamine Oxidase and Phenolsulfotransferase and Plasma Levels of Acid Metabolites in Aggressive and Non-aggressive Prisoners and Children withAttention Deficit Disorders.- Trace Indoleamines in the Central Nervous System.- Tryptamine Kinetics in Healthy Volunteers.- Elevated Phenylethylamine Excretion in Women.- Phenylethylamine and Personality.- Trace Amines/Metabolite Responses in Stress.- The Adrenaline Hypothesis of Essential Hypertension: An Investigation in Patients and Controls of the MCR Hypertension Trial.- Tyramine Kinetics Before and After MAO Inhibition with the Reversible MAO-A Inhibitor Brofaremine (CGP 11 305 R).- Tyramine-Conjugation Deficit as a Trait-Marker in Endogenous Depressive Illness.- The Origin of Central and Peripheral ?-Hydroxyphenylacetic Acid in Man and Rats.- Free Communications.- Urinary Excretion of Tryptamine, MHPG, HVA, VMA, and HIAA by Volunteers Treated with CGP 4718, a Combined Inhibitor of MAO-A and 5-HT Uptake.- Study of the Synaptosomal Catecholamine Uptake in Postmortem Brain of Schizophrenics.- A Physicochemical Approoch to Characterize [3H]Tryptamine Binding Sites in Human Brain.- Phenylethylamine is Hydroxylated and n-Methylated by In Vitro Human Brain Preparations.- List of Abbreviations.