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Beskrivning
Internationally recognized investigators review the latest developments in, and novel approaches to, understanding the prion protein and prion diseases at the molecular level.
What Would Thomas Henry Huxley Have Made of Prion Diseases?.- Prion Protein as Copper-Binding Protein at the Synapse.- A Function for the Prion Protein?.- Prion Protein Peptide.- Characterization of Bovine Spongiform Encephalopathy and Scrapie Strains/Isolates by Immunochemical Analysis of PrPSc.- Differential Targeting of Neurons by Prion Strains.- Transgenic Studies of Prion Diseases.- Prions: From Neurografts to Neuroinvasion.- Cellular and Transgenic Models of Familial Prion Diseases.- Central Nervous System Inflammation and Prion Disease Pathogenesis.- The Electroneuropathology of Prion Disease.- Transmissible Spongiform Encephalopathy Neurobiology and Ultrastructure Suggests Extracellular PrPSc Conversion Consistent with Classical Amyloidosis.- Conformation as Therapeutic Target in the Prionoses and Other Neurodegenerative Conditions.- Prions of Yeast From Cytoplasmic Genes to Heritable Amyloidosis.
