Methods in Molecular Medicine – serie
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237 produkter
Prion Diseases
Av Harry F. Baker, Rosalind M. Ridley
Inbunden, 1996
1690 kr
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Leading researchers and clinicians describe their state-of-the-art findings and hypotheses arising from a variety of different approaches to this group of diseases. Their approaches include clinical presentations, epidemiology, transgenic methods, and diagnostic tests via transmission electron …
Herpes Simplex Virus Protocols
Av S. Moira Brown, Alasdair R. MacLean
Inbunden, 1997
1129 kr
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An outstanding collection of state-of-the-art experimental methods for herpes virology. These procedures range from the more biological in vivo maneuvers to the purely molecular, and are described in detail by selected experts to ensure reproducibility. Most of the protocols rely on the herpes …
Clinical Applications of PCR
Av Y. M. Dennis Lo, Y. M. Dennis Lo
Häftad, 1998
1690 kr
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The polymerase chain reaction (PCR) is one of the most important molecular biological methods ever devised, with numerous applications to cli- cal molecular medicine. Since its description in 1985, PCR has undergone tremendous improvements, and many variations on the basic PCR theme have been …
Tumor Marker Protocols
Av Margaret Hanausek, Zbigniew Walaszek
Inbunden, 1998
1690 kr
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A much-needed collection of cutting-edge methods for the detection and discovery of new cancer markers, particularly molecular tumor markers. Each method is fully described by a hands-on expert who regularly uses it in the laboratory and has perfected it to a high degree of ready reproducibility. …
Helicobacter pylori Protocols
Av Christopher L. Clayton, Harry L. T. Mobley
Inbunden, 1997
1129 kr
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Helicobacter pylori Protocols offers an outstanding collection of state-of-the-art protocols for the identification and molecular manipulation of H. pylori. The authoritative contributors supply detailed and readily reproducible protocols for the culturing of H. pylori, for the isolation and …
Lectin Methods and Protocols
Av Jonathan M. Rhodes, Jeremy D. Milton
Inbunden, 1997
1690 kr
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Lectins have in the past been regarded by many scientists as curious proteins of uncertain structure and specificity that bind to carbohydrates of dubious significance themselves. All this is rapidly changing. The functional importance of glycosylation in cell-cell and cell-pathogen interactions, …
Diagnostic Virology Protocols
Av John R. Stephenson, Alan Warnes
Häftad, 1998
1241 kr
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The accurate and reliable diagnosis of transmissible diseases is the most powerful weapon available to ensure their control, and in some cases eradication. The detection of parasites in clinical cases, companion and farm animals, and in the environment is relatively easy since many of them are …
Hemostasis and Thrombosis Protocols
Av David J. Perry, K. John Pasi
Inbunden, 1999
1129 kr
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Laboratory studies in hemostasis have traditionally focused on abn- malities of platelet function or the quantitative and qualitative disorders that affect the proteins involved in blood coagulation. However, over the last 10 years there has been an explosion in our understanding of the molecular …
Therapeutic Applications of Ribozymes
Inbunden, 1998
1129 kr
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Expert laboratory scientists describe in detail their methodologies for constructing ribozymes designed to elucidate the role of specific genes as key routes to the development of novel therapies for a wide variety of diseases. The authors review the many sites targeted with ribozymes in various …
Diagnostic Virology Protocols
Av John R. Stephenson, Alan Warnes
Inbunden, 1998
1690 kr
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A collection of cutting-edge techniques for detecting most of the major viruses that afflict mankind, including influenza, hepatitis, herpes, polio, mumps, HIV, and many more. The techniques are well-tested, easily reproducible, and readily employ all the new technologies - PCR, RIA, ELISA, and …
Molecular Bacteriology: Protocols and Clinical Applications
Av Neil Woodford, Alan Johnson
Inbunden, 1998
1690 kr
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The enormous advances in molecular biology that have been witnessed in . Not recent years have had major impacts on many areas of the biological sciences least of these has been in the field of clinical bacteriology and infectious disease . Molecular Bacteriology: Protocols and ClinicalApplications …
Clinical Applications of PCR
Inbunden, 1998
1690 kr
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An unprecedented collection of core PCR techniques useful for the study and diagnosis of human diseases. Cutting-edge and essential for today's diagnostic laboratories, these techniques heavily utilize nonisotopic, solution phase, and in situ amplification methods. A significant number of chapters …
Peptidomimetics Protocols
Inbunden, 1998
1129 kr
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A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds, turn mimetics, peptide-bound replacements, and enzyme inhibitors. Topics range from unusual syntheses of amino acids to the use of a variety of linear and heterocyclic scaffolds in place of the …
Drug Targeting
Strategies, Principles, and Applications
Inbunden, 2000
1129 kr
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G. E. Francis and Cristina Delgado have assembled a comprehensive collection of leading-edge protocols for drug targeting studies. In addition to the detailed step-by-step instruction, the protocols review the principal current targeting strategies, discuss how to build the constructs, examine …
Sexually Transmitted Diseases
Av Rosanna Peeling, P. Frederick Sparling
Inbunden, 1998
1129 kr
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In recent years, molecular techniques have enhanced our ability to detect sexually transmitted infections and to conduct research to further our und- standing of sexually transmitted diseases. Molecular methods to quantitate pathogen load have also been shown to be useful for the management of HIV …
Hematologic Malignancies
Methods and Techniques
Inbunden, 2000
1129 kr
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In Hematologic Malignancies: Methods and Techniques, a panel of acknowledged experts review many of the key molecular methods used for the diagnosis and subsequent management of hematologic malignancies. These clinically relevant techniques range from routine test procedures to highly sophisticated …
Antiviral Methods and Protocols
Av Derek Kinchington, Raymond F. Schinazi
Inbunden, 1999
1129 kr
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Experienced scientists describe - in an easily-followed format - their state-of-the-art techniques for evaluating antiviral compounds. The assays described include systems for investigating drugs used against herpesviruses, hepatitis viruses, human immunodeficiency viruses, human papillomaviruses, …
DNA Vaccines
Methods and Protocols
Av Douglas B. Lowrie, Robert Whalen
Inbunden, 1999
2250 kr
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The field of DNA vaccines has undergone explosive growth in the last few years. As usual, some historical precursors of this approach can be d- cerned in the scientific literature of the last decades. However, the present state of affairs appears to date from observations made discreetly in 1988 by …
Aging Methods and Protocols
Av Yvonne A. Barnett, Christopher R. Barnett
Inbunden, 2000
1129 kr
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Aging is an almost universal process within biological systems, one which leads to a decline in functional capacity, disease onset, and eventually death. There has been much interest in recent years to elucidate the molecular mec- nisms that underlie the aging process. Many theories have been …
Ovarian Cancer
Methods and Protocols
Inbunden, 2000
2250 kr
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Over one hundred well-respected scientists comprehensively review every aspect of the biology underlying ovarian cancer and present a remarkably detailed collection of easy-to-follow methods for illuminating basic mechanisms underlying all forms of cancer. Here today's investigators will find the …
Cytotoxic Drug Resistance Mechanisms
Av Robert Brown, Uta Böger-Brown
Inbunden, 1999
1129 kr
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Leading clinical and laboratory scientists describe cutting-edge methods for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumors. The protocols contain detailed instructions and extensive troubleshooting tips that allow researchers effectively to study a wide …
Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery
Electrically Mediated Delivery of Molecules to Cells
Inbunden, 2000
1690 kr
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Leading experts comprehensively review all aspects of the delivery of therapeutic molecules to cells using electrical impulses - i.e., the extraordinarily promising new areas of electrogenetherapy, electrochemotherapy, and transdermal drug delivery. Their survey ranges from outlines of the basic …
Neurodegeneration Methods and Protocols
Inbunden, 1998
1129 kr
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An outstanding collection of detailed, state-of-the-art techniques for studying many aspects of nervous system cell biology. The methods span a multidisciplinary range of cellular and molecular approaches to both normal and injured nervous system function, and particularly to neurodegenerative …
Molecular Analysis of Cancer
Av Jacqueline Boultwood, Carrie Fidler
Inbunden, 2001
1690 kr
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Over the past 20 years, technological advances in molecular biology have proven invaluable to the understanding of the pathogenesis of human cancer. The application of molecular technology to the study of cancer has not only led to advances in tumor diagnosis, but has also provided markers for the …
Asthma
Inbunden, 2000
1129 kr
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Asthma has rapidly become one of the most common chronic illnesses of the Western world, and its prevalence continues to rise, with the proportion of patients with more severe diseases also increasing. Faced with this problem, more researchers are focusing on the causes, mechanisms, and …
Clinical Applications of Capillary Electrophoresis
Inbunden, 1999
1129 kr
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The term "electrophoresis" was first used by Michaelis in 1909, to - scribe the migration of colloids in an electric field. The first practical elect- phoresis method was described by Tiselius in 1937. He used a U-tube filled with buffer layered on top of sample; migration could be monitored using …
Celiac Disease
Methods and Protocols
Inbunden, 2000
1690 kr
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Research into gluten sensitivity has never been more popular nor more exciting. Thus a call for a new book, Celiac Disease: Methods and Protocols, devoted entirely to techniques and technology seemed a most appropriate undertaking. I am therefore grateful to Professor J. M. Walker for inviting me …
Molecular Pathology Protocols
Av Anthony A. Killeen, Anthony A. Killeen
Inbunden, 2000
1690 kr
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The era of molecular pathology has arrived. From its promising beg- nings in research laboratories, the field has grown, and continues to grow, to become a vital part of the care of an ever-increasing number of patients. Because of its recent emergence from the research taboratory, many molecuIar …
Melanoma Techniques and Protocols
Molecular Diagnosis, Treatment, and Monitoring
Inbunden, 2001
1690 kr
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This book is about melanoma—its biology, immunology, and pathology, as well as the initial use of powerful genomic tools to study its fundamental mole- lar and genetic characteristics. The study of cancer will be profoundly impacted by the Human Genome Project. I would like to discuss some of these …
Muscular Dystrophy
Methods and Protocols
Av Katherine M.D. Bushby, Louise V.B. Anderson
Inbunden, 2001
1690 kr
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Katherine Bushby and Louise Anderson assemble an outstanding collection of key techniques for the analysis of DNA and protein from patients suspected to suffer from muscular dystrophy. Each method is highly detailed to ensure success and is presented by a hands-on expert. The various DNA techniques …
