Pathway for an Adult Patient with a Primary Brain Tumour

Primary brain tumours in adults encompass a spectrum of intra-axial and extra-axial neoplasms, each with distinct histological, molecular and prognostic characteristics. The clinical presentation of these tumours can vary widely: some are detected incidentally; others are identified on brain imaging requested to investigate clinical symptoms relating to raised intracranial pressure, seizures or focal neurological deficits. This Element outlines a structured clinical approach to diagnosis and initial management of adult patients presenting acutely with a primary brain tumour. Clinical case scenarios are integrated throughout the chapter to apply this knowledge. These are complemented by an overview of common 'pearls and pitfalls' in this clinical domain.