Gene Delivery

Nanotechnology and Therapeutic Applications

AvYashwant Pathak

Inbunden, Engelska, 2022

Del i serien Drugs and the Pharmaceutical Sciences

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Beskrivning

Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery. Additional features include" Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing. Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize. Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario Discusses siRNA, mRNA, and DNA plasmids.

Produktinformation

Utgivningsdatum:2022-06-29
Mått:178 x 254 x 18 mm
Vikt:620 g
Format:Inbunden
Språk:Engelska
Serie:Drugs and the Pharmaceutical Sciences
Antal sidor:232
Förlag:Taylor & Francis Ltd
ISBN:9781032025544

Utforska kategorier

Farmakologi inom Medicin
Teknik: allmänt inom Naturvetenskap och teknik
Biokemisk teknik inom Naturvetenskap och teknik

Mer om författaren

Dr. Yashwant Pathak completed his Ph.D. in Pharmaceutical Technology from Nagpur University,India and his EMBA MS in Conflict Management from Sullivan University. He is Professor andAssociate Dean for Faculty Affairs at the College of Pharmacy, University of South Florida. Tampa,Florida. With extensive experience in academia as well as industry, he has more than 100 publications,two patents and two patent applications, twenty edited books published, including seven booksin Nanotechnology and six in Nutraceuticals and drug delivery systems. He has several books in culturalstudies and conflict management. He has received several National and International awards.His recent assignment was Fulbright Senior Fellow in Indonesia for six months, where he traveledin seven countries and lectured in more than twenty universities. He was a key note speaker at theWorld Hindu Wisdom meeting in Bali, Indonesia, in June 2017 and co-chaired with the Governorof Bali. Dr Yashwant Pathak is also a Professor of Global Health with the College of Public Healthat USF. Recently, his student completed a PhD in Global Health on homeopathy medicine and itsefficacy, a survey of 1274 patients in Pune in India. Dr Pathak is also an adjunct faculty member atAirLangga University College of Public Health at Surabaya Indonesia.

Recensioner i media

"This book succeeds in presenting the challenges and barriers facing the field of nucleic acid delivery for therapeutic purposes, as well as the current status and main achievements of existing nanotechnologies in different therapeuticareas".- Doody's Review

Innehållsförteckning

Chapter 01Challenges in delivering gene therapyChapter 02Advances in genome editing: the technology of choice for precise and efficient disease treatment, with special focus on nano delivery systemsChapter 03Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapyChapter 04Green nanoparticles for oligonucleotide deliveryChapter 05Development of mRNA vaccines for Covid -19 in challenging Pandemic scenarioChapter 06Gene therapy for cardiovascular diseases: clinical evidencesChapter 07Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDSChapter 08siRNA delivery for therapeutic applications using nanoparticlesChapter 09Clinical perspectives on Gene therapy for retina and eye diseasesChapter 10Herpesvirus microRNAs for use in gene therapy immune-evasion strategiesChapter 11siRNA delivery for therapeutic applications using nanoparticlesChapter 12Gene therapy and small molecule treatment for cystic fibrosisChapter 13CRISPR gene therapy recent trends and clinical applicationsChapter 14Clinical applications of gene therapy for Immuno-deficienciesChapter 15Regulatory challenges for nano gene delivery