Antisense Drug Technology

Principles, Strategies, and Applications, Second Edition

AvStanley T. Crooke

E-bok

Engelska, 2007

6 181 kr

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Beskrivning

Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generati

Produktinformation

Utgivningsdatum:2007-07-25
Språk:Engelska
Kopieringsskydd:LCP
ISBN:9781040078716
Förlag:Taylor & Francis Ltd
Upplaga:2

Utforska kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Farmakologi inom Medicin
Kemi inom Naturvetenskap och teknik

Recensioner i media

This book gives a nearly complete overview of the current state-of-the-art oligonucleotide drugs. … provides valuable insights into the great opportunities that are presented by this technology.—Dr. Kees Fluiter, The University of Amsterdam, in ChemMedChem, Vol. 4, 2009This edition is a cutting edge document including up-to-date cited references and a variety of compelling clinical case studies, and it of course retains the superb basic principles and background to antisense drug technologies featured in the first edition.—Gary Evans, Industrial Research Ltd., in Journal of Medicinal Chemistry, 2008, Vol. 51, No. 5

Innehållsförteckning

Introduction, The Basics of Oligonucleotide-Based Therapeutics, Hybridization-Based Drugs: Basic Properties 2_-O-Methoxyethyl Oligonucleotides, Hybridization-Based Drugs: Basic Properties Duplex RNA Drugs, Other Chemical Classes of Drugs, Therapeutic Applications, Index