Ana Luisa Neves (MD, MSc, PhD) is a Associate Professor in Digital Health at Imperial College London. Dr Neves is a practicing GP, and currently holds roles as Chair of the Working Party on eHealth of WONCA World and Vice-Chair of the European General Practice Research Network. At Imperial, Dr Ana Luisa Neves is Director of the Global Digital Health, leads the Digital Health Theme at the Northwest London NIHR Applied Research Collaboration, and is Co-Lead for the Theme ‘New service delivery models’ at the Northwest London NIHR Patient Safety Research Centre. She also holds a position as Associate Professor at University of Porto. She coordinates multidisciplinary research teams focusing on the design, implementation and evaluation of digital technologies to deliver safer, more effective, and patientcentred care.Dr. Neves has a Master of Science from University of Porto (Portugal) and a PhD in Clinical Medicine from Imperial College London (UK). During her PhD, she received a PhD studentship from the GABBA Program (Graduate Program in Areas of Basic and Applied Biology), a international PhD program funded by the Portuguese Foundation for Science and Technology. In 2018, Dr. Neves was awarded a WONCA Scholarship, followed by an Athena SWAN Award for Excellence at Imperial College London in 2019. She completed the Global Health Leaders Program at Harvard University in 2022–2023. Dr Neves was appointed as a Visiting Scholar at the Harvard T.H. Chan School of Public Health (2024–2025), as part of her International Fellowship at Ariadne Labs. Dr Neves has more than 6,500 citations, with a h-index=32.Liliana Laranjo (MD, MPH, PhD) is an Associate Professor at Sydney Medical School, University of Sydney, where she holds a Sydney Horizon Fellowship. She has a background as a General Practitioner and is Deputy Chair of the World Organization of General Practitioners’ (WONCA) eHealth Working Party, as well as Member of the founding International Advisory Board for The Lancet Primary Care. Dr. Laranjo leads the Digital Health Stream at the Westmead Applied Research Centre, an Impact Centre of the University of Sydney, where she coordinates several clinical trials and leads multidisciplinary teams across different fields, from medicine and health to data science and engineering. Her research focuses on leveraging Digital Health to empower and support patients in their health journeys, with the aim of preventing chronic disease at scale in the community.Dr. Laranjo has a Master of Public Health from Harvard University and a PhD in Medicine (Digital Health) from Lisbon Medical School, Portugal. During her PhD, she received a Junior Clinical Research Award from the Harvard Medical School-Portugal Program. She was a 2022 World Heart Federation Emerging Leader and has been awarded a National Health and Medical Research Council Emerging Leader Investigator Grant (2023–2027) and an Honorary Future Leader Fellowship from the National Heart Foundation (2023–2026) in Australia. Dr. Laranjo’s work has received global media attention and has been used to guide research, practice, and policy worldwide. Her field-weighted citation index is 2, meaning her overall number of citations is double the world average in the field.

• ForewordChapter 1 Understanding Digital Health in Primary CareChai Carol Chan, Jako Burgers, Pramendra Prasad, Mehmet Ungan, Karen Kinder, Azeem Majeed and Ana Luisa Neves Chapter 2 Digital Health Tools for Clinical Practice Edmond Li, Olivia Lounsbury, Bernardo Sousa-Pinto, Unben Pillay, Avivit Golan Cohen and Shlomo VinkerChapter 3 The Role of Digital Health in Patient-Centered CareKeith Thompson, Hüsna Sarıca Çevik, Hans Eguia, Bridget L. Ryan, Moira Stewart and Tom Freeman Chapter 4 Improving Clinical Effectiveness Through Digital Interventions Nana Kwame Ayisi-Boateng, Eric Kojo Nsa Oduro, Obed Kwabena Offe Amponsah, Douglas Aninng Opoku, Jacopo Demurtas and Benedict Hayhoe Chapter 5 Safety and Unintended ConsequencesUlrik Bak Kirk, Rebecca Payne, Ana Ferreira, Andree Rochfort and Nancy MatillyaChapter 6 Equity and Digital DivideSteven van de Vijver, Paulien Tensen, Raquel Gómez Bravo, Francisca Gaifém, Pratyush Kumar and Mercy WanjalaChapter 7 User-Centred Design and User Experiences with Digital HealthGeva Greenfield, Ana Rita Luz, Boon How Chew, Kam Cheong Wong and Cristina JácomeChapter 8 Implementing Digital Health Solutions in Primary CareGeronimo Jimenez, Marise Kasteleyn, Niels Chavannes, Raluca Zoițanu, Ahmed Alboksmaty Chapter 9 Digital Health Sustainability and Systems Thinking ApproachesNick Guldemond, Melita Sogomonjan and Mariam BeridzeChapter 10 Conclusion: Transforming Primary Care Through Digital Health Liliana Laranjo, Sara Ares-Blanco, Amanda Howe, Sankha Randenikumara and Donald LiIndex

Ana Luisa Neves (MD, MSc, PhD) is a Associate Professor in Digital Health at Imperial College London. Dr Neves is a practicing GP, and currently holds roles as Chair of the Working Party on eHealth of WONCA World and Vice-Chair of the European General Practice Research Network. At Imperial, Dr Ana Luisa Neves is Director of the Global Digital Health, leads the Digital Health Theme at the Northwest London NIHR Applied Research Collaboration, and is Co-Lead for the Theme ‘New service delivery models’ at the Northwest London NIHR Patient Safety Research Centre. She also holds a position as Associate Professor at University of Porto. She coordinates multidisciplinary research teams focusing on the design, implementation and evaluation of digital technologies to deliver safer, more effective, and patientcentred care.Dr. Neves has a Master of Science from University of Porto (Portugal) and a PhD in Clinical Medicine from Imperial College London (UK). During her PhD, she received a PhD studentship from the GABBA Program (Graduate Program in Areas of Basic and Applied Biology), a international PhD program funded by the Portuguese Foundation for Science and Technology. In 2018, Dr. Neves was awarded a WONCA Scholarship, followed by an Athena SWAN Award for Excellence at Imperial College London in 2019. She completed the Global Health Leaders Program at Harvard University in 2022–2023. Dr Neves was appointed as a Visiting Scholar at the Harvard T.H. Chan School of Public Health (2024–2025), as part of her International Fellowship at Ariadne Labs. Dr Neves has more than 6,500 citations, with a h-index=32.Liliana Laranjo (MD, MPH, PhD) is an Associate Professor at Sydney Medical School, University of Sydney, where she holds a Sydney Horizon Fellowship. She has a background as a General Practitioner and is Deputy Chair of the World Organization of General Practitioners’ (WONCA) eHealth Working Party, as well as Member of the founding International Advisory Board for The Lancet Primary Care. Dr. Laranjo leads the Digital Health Stream at the Westmead Applied Research Centre, an Impact Centre of the University of Sydney, where she coordinates several clinical trials and leads multidisciplinary teams across different fields, from medicine and health to data science and engineering. Her research focuses on leveraging Digital Health to empower and support patients in their health journeys, with the aim of preventing chronic disease at scale in the community.Dr. Laranjo has a Master of Public Health from Harvard University and a PhD in Medicine (Digital Health) from Lisbon Medical School, Portugal. During her PhD, she received a Junior Clinical Research Award from the Harvard Medical School-Portugal Program. She was a 2022 World Heart Federation Emerging Leader and has been awarded a National Health and Medical Research Council Emerging Leader Investigator Grant (2023–2027) and an Honorary Future Leader Fellowship from the National Heart Foundation (2023–2026) in Australia. Dr. Laranjo’s work has received global media attention and has been used to guide research, practice, and policy worldwide. Her field-weighted citation index is 2, meaning her overall number of citations is double the world average in the field.

• ForewordChapter 1 Understanding Digital Health in Primary CareChai Carol Chan, Jako Burgers, Pramendra Prasad, Mehmet Ungan, Karen Kinder, Azeem Majeed and Ana Luisa Neves Chapter 2 Digital Health Tools for Clinical Practice Edmond Li, Olivia Lounsbury, Bernardo Sousa-Pinto, Unben Pillay, Avivit Golan Cohen and Shlomo VinkerChapter 3 The Role of Digital Health in Patient-Centered CareKeith Thompson, Hüsna Sarıca Çevik, Hans Eguia, Bridget L. Ryan, Moira Stewart and Tom Freeman Chapter 4 Improving Clinical Effectiveness Through Digital Interventions Nana Kwame Ayisi-Boateng, Eric Kojo Nsa Oduro, Obed Kwabena Offe Amponsah, Douglas Aninng Opoku, Jacopo Demurtas and Benedict Hayhoe Chapter 5 Safety and Unintended ConsequencesUlrik Bak Kirk, Rebecca Payne, Ana Ferreira, Andree Rochfort and Nancy MatillyaChapter 6 Equity and Digital DivideSteven van de Vijver, Paulien Tensen, Raquel Gómez Bravo, Francisca Gaifém, Pratyush Kumar and Mercy WanjalaChapter 7 User-Centred Design and User Experiences with Digital HealthGeva Greenfield, Ana Rita Luz, Boon How Chew, Kam Cheong Wong and Cristina JácomeChapter 8 Implementing Digital Health Solutions in Primary CareGeronimo Jimenez, Marise Kasteleyn, Niels Chavannes, Raluca Zoițanu, Ahmed Alboksmaty Chapter 9 Digital Health Sustainability and Systems Thinking ApproachesNick Guldemond, Melita Sogomonjan and Mariam BeridzeChapter 10 Conclusion: Transforming Primary Care Through Digital Health Liliana Laranjo, Sara Ares-Blanco, Amanda Howe, Sankha Randenikumara and Donald LiIndex

Ana Luisa Neves (MD, MSc, PhD) is a Associate Professor in Digital Health at Imperial College London. Dr Neves is a practicing GP, and currently holds roles as Chair of the Working Party on eHealth of WONCA World and Vice-Chair of the European General Practice Research Network. At Imperial, Dr Ana Luisa Neves is Director of the Global Digital Health, leads the Digital Health Theme at the Northwest London NIHR Applied Research Collaboration, and is Co-Lead for the Theme ‘New service delivery models’ at the Northwest London NIHR Patient Safety Research Centre. She also holds a position as Associate Professor at University of Porto. She coordinates multidisciplinary research teams focusing on the design, implementation and evaluation of digital technologies to deliver safer, more effective, and patientcentred care.Dr. Neves has a Master of Science from University of Porto (Portugal) and a PhD in Clinical Medicine from Imperial College London (UK). During her PhD, she received a PhD studentship from the GABBA Program (Graduate Program in Areas of Basic and Applied Biology), a international PhD program funded by the Portuguese Foundation for Science and Technology. In 2018, Dr. Neves was awarded a WONCA Scholarship, followed by an Athena SWAN Award for Excellence at Imperial College London in 2019. She completed the Global Health Leaders Program at Harvard University in 2022–2023. Dr Neves was appointed as a Visiting Scholar at the Harvard T.H. Chan School of Public Health (2024–2025), as part of her International Fellowship at Ariadne Labs. Dr Neves has more than 6,500 citations, with a h-index=32.Liliana Laranjo (MD, MPH, PhD) is an Associate Professor at Sydney Medical School, University of Sydney, where she holds a Sydney Horizon Fellowship. She has a background as a General Practitioner and is Deputy Chair of the World Organization of General Practitioners’ (WONCA) eHealth Working Party, as well as Member of the founding International Advisory Board for The Lancet Primary Care. Dr. Laranjo leads the Digital Health Stream at the Westmead Applied Research Centre, an Impact Centre of the University of Sydney, where she coordinates several clinical trials and leads multidisciplinary teams across different fields, from medicine and health to data science and engineering. Her research focuses on leveraging Digital Health to empower and support patients in their health journeys, with the aim of preventing chronic disease at scale in the community.Dr. Laranjo has a Master of Public Health from Harvard University and a PhD in Medicine (Digital Health) from Lisbon Medical School, Portugal. During her PhD, she received a Junior Clinical Research Award from the Harvard Medical School-Portugal Program. She was a 2022 World Heart Federation Emerging Leader and has been awarded a National Health and Medical Research Council Emerging Leader Investigator Grant (2023–2027) and an Honorary Future Leader Fellowship from the National Heart Foundation (2023–2026) in Australia. Dr. Laranjo’s work has received global media attention and has been used to guide research, practice, and policy worldwide. Her field-weighted citation index is 2, meaning her overall number of citations is double the world average in the field.

• ForewordChapter 1 Understanding Digital Health in Primary CareChai Carol Chan, Jako Burgers, Pramendra Prasad, Mehmet Ungan, Karen Kinder, Azeem Majeed and Ana Luisa Neves Chapter 2 Digital Health Tools for Clinical Practice Edmond Li, Olivia Lounsbury, Bernardo Sousa-Pinto, Unben Pillay, Avivit Golan Cohen and Shlomo VinkerChapter 3 The Role of Digital Health in Patient-Centered CareKeith Thompson, Hüsna Sarıca Çevik, Hans Eguia, Bridget L. Ryan, Moira Stewart and Tom Freeman Chapter 4 Improving Clinical Effectiveness Through Digital Interventions Nana Kwame Ayisi-Boateng, Eric Kojo Nsa Oduro, Obed Kwabena Offe Amponsah, Douglas Aninng Opoku, Jacopo Demurtas and Benedict Hayhoe Chapter 5 Safety and Unintended ConsequencesUlrik Bak Kirk, Rebecca Payne, Ana Ferreira, Andree Rochfort and Nancy MatillyaChapter 6 Equity and Digital DivideSteven van de Vijver, Paulien Tensen, Raquel Gómez Bravo, Francisca Gaifém, Pratyush Kumar and Mercy WanjalaChapter 7 User-Centred Design and User Experiences with Digital HealthGeva Greenfield, Ana Rita Luz, Boon How Chew, Kam Cheong Wong and Cristina JácomeChapter 8 Implementing Digital Health Solutions in Primary CareGeronimo Jimenez, Marise Kasteleyn, Niels Chavannes, Raluca Zoițanu, Ahmed Alboksmaty Chapter 9 Digital Health Sustainability and Systems Thinking ApproachesNick Guldemond, Melita Sogomonjan and Mariam BeridzeChapter 10 Conclusion: Transforming Primary Care Through Digital Health Liliana Laranjo, Sara Ares-Blanco, Amanda Howe, Sankha Randenikumara and Donald LiIndex