Thomas Klein is an artificial intelligence expert and Director of Technology Strategy at Microsoft. Based in the United States, he supports major organizations in their strategic adoption of AI, with particular expertise in the digital transformation of the healthcare sector.A graduate of Télécom Nancy, one of France’s leading engineering schools, Thomas Klein completed his education in the United Kingdom at the University of Leicester. He later trained in artificial intelligence applied to healthcare through Executive Education programs at MIT and Harvard, deepening the expertise he had built through years of hands-on project work in hospitals and healthcare organizations.He began his career as a consultant, contributing to major digital transformation projects for the French government, and went on to serve as Director of Digital Transformation, leading projects for European institutions. His commitment to AI in healthcare took concrete form with the implementation of the world’s first solution combining mixed reality and artificial intelligence to help children with autism develop their social skills, an innovation that reflects his conviction that technology should serve human well-being and inclusion.Thomas Klein joined Microsoft France in 2020, at a moment when the acceleration of AI placed his expertise at the center of a rapidly evolving field. His work there earned him several awards, including the Platinum Award and the Technology Solution Excellence Award, recognizing his ability to orchestrate complex transformations and guide organizations toward successful AI adoption in healthcare. He has presented his vision of AI in hospitals at HIMSS, the world’s leading healthcare technology conference.Alongside his role at Microsoft, he served as a city councilor in Suresnes, France, appointed by the Mayor with responsibility for Responsible Artificial Intelligence. In this role, he led a pioneering effort to integrate AI into local public services and organized the first symposium on “AI and My City,” an experience that gave him a firsthand understanding of the challenges of accessibility and ethics in bringing AI to all citizens.Based in the United States since 2024, Thomas Klein now works with organizations around the world to build strategic, responsible approaches to AI and to ensure that these technologies deliver on their potential. He is guided by a simple conviction: technology must serve humanity, not the reverse. This unique combination positions him as a leading voice at the forefront of artificial intelligence and its profound transformation of the healthcare landscape.

• PART A: FUNDAMENTALS Chapter 1. Understanding the acceleration of Artificial Intelligence Chapter 2. The AI Agentic paradigm Chapter 3. AI in Healthcare: a delicate revolution with high stakes Chapter 4. Medical data: fueling innovation in healthcare PART B: REAL-WORLD APPLICATIONS Chapter 5. Revolutionizing diagnosis and medical imaging Chapter 6. Predictive medicine: anticipating to save lives Chapter 7. AI agentic approach to revolutionize personalized care Chapter 8. Connected health: a digital revolution for all Chapter 9. AI serving hospitals Chapter 10. Digital therapies: a new era for mental health Chapter 11. AI and disability: towards greater autonomy PART C: RESPONSIBLE IMPLEMENTATION Chapter 12. Building trust: ethics at the heart of AI in healthcare Chapter 13. Cybersecurity and AI Chapter 14. Emerging technologies and the future of healthcare Chapter 15. The support system: AI powering what happens before and around care CONCLUSION: Together for Tomorrow’s Health

Thomas Klein is an artificial intelligence expert and Director of Technology Strategy at Microsoft. Based in the United States, he supports major organizations in their strategic adoption of AI, with particular expertise in the digital transformation of the healthcare sector.A graduate of Télécom Nancy, one of France’s leading engineering schools, Thomas Klein completed his education in the United Kingdom at the University of Leicester. He later trained in artificial intelligence applied to healthcare through Executive Education programs at MIT and Harvard, deepening the expertise he had built through years of hands-on project work in hospitals and healthcare organizations.He began his career as a consultant, contributing to major digital transformation projects for the French government, and went on to serve as Director of Digital Transformation, leading projects for European institutions. His commitment to AI in healthcare took concrete form with the implementation of the world’s first solution combining mixed reality and artificial intelligence to help children with autism develop their social skills, an innovation that reflects his conviction that technology should serve human well-being and inclusion.Thomas Klein joined Microsoft France in 2020, at a moment when the acceleration of AI placed his expertise at the center of a rapidly evolving field. His work there earned him several awards, including the Platinum Award and the Technology Solution Excellence Award, recognizing his ability to orchestrate complex transformations and guide organizations toward successful AI adoption in healthcare. He has presented his vision of AI in hospitals at HIMSS, the world’s leading healthcare technology conference.Alongside his role at Microsoft, he served as a city councilor in Suresnes, France, appointed by the Mayor with responsibility for Responsible Artificial Intelligence. In this role, he led a pioneering effort to integrate AI into local public services and organized the first symposium on “AI and My City,” an experience that gave him a firsthand understanding of the challenges of accessibility and ethics in bringing AI to all citizens.Based in the United States since 2024, Thomas Klein now works with organizations around the world to build strategic, responsible approaches to AI and to ensure that these technologies deliver on their potential. He is guided by a simple conviction: technology must serve humanity, not the reverse. This unique combination positions him as a leading voice at the forefront of artificial intelligence and its profound transformation of the healthcare landscape.

• PART A: FUNDAMENTALS Chapter 1. Understanding the acceleration of Artificial Intelligence Chapter 2. The AI Agentic paradigm Chapter 3. AI in Healthcare: a delicate revolution with high stakes Chapter 4. Medical data: fueling innovation in healthcare PART B: REAL-WORLD APPLICATIONS Chapter 5. Revolutionizing diagnosis and medical imaging Chapter 6. Predictive medicine: anticipating to save lives Chapter 7. AI agentic approach to revolutionize personalized care Chapter 8. Connected health: a digital revolution for all Chapter 9. AI serving hospitals Chapter 10. Digital therapies: a new era for mental health Chapter 11. AI and disability: towards greater autonomy PART C: RESPONSIBLE IMPLEMENTATION Chapter 12. Building trust: ethics at the heart of AI in healthcare Chapter 13. Cybersecurity and AI Chapter 14. Emerging technologies and the future of healthcare Chapter 15. The support system: AI powering what happens before and around care CONCLUSION: Together for Tomorrow’s Health

Thomas Klein is an artificial intelligence expert and Director of Technology Strategy at Microsoft. Based in the United States, he supports major organizations in their strategic adoption of AI, with particular expertise in the digital transformation of the healthcare sector.A graduate of Télécom Nancy, one of France’s leading engineering schools, Thomas Klein completed his education in the United Kingdom at the University of Leicester. He later trained in artificial intelligence applied to healthcare through Executive Education programs at MIT and Harvard, deepening the expertise he had built through years of hands-on project work in hospitals and healthcare organizations.He began his career as a consultant, contributing to major digital transformation projects for the French government, and went on to serve as Director of Digital Transformation, leading projects for European institutions. His commitment to AI in healthcare took concrete form with the implementation of the world’s first solution combining mixed reality and artificial intelligence to help children with autism develop their social skills, an innovation that reflects his conviction that technology should serve human well-being and inclusion.Thomas Klein joined Microsoft France in 2020, at a moment when the acceleration of AI placed his expertise at the center of a rapidly evolving field. His work there earned him several awards, including the Platinum Award and the Technology Solution Excellence Award, recognizing his ability to orchestrate complex transformations and guide organizations toward successful AI adoption in healthcare. He has presented his vision of AI in hospitals at HIMSS, the world’s leading healthcare technology conference.Alongside his role at Microsoft, he served as a city councilor in Suresnes, France, appointed by the Mayor with responsibility for Responsible Artificial Intelligence. In this role, he led a pioneering effort to integrate AI into local public services and organized the first symposium on “AI and My City,” an experience that gave him a firsthand understanding of the challenges of accessibility and ethics in bringing AI to all citizens.Based in the United States since 2024, Thomas Klein now works with organizations around the world to build strategic, responsible approaches to AI and to ensure that these technologies deliver on their potential. He is guided by a simple conviction: technology must serve humanity, not the reverse. This unique combination positions him as a leading voice at the forefront of artificial intelligence and its profound transformation of the healthcare landscape.

• PART A: FUNDAMENTALS Chapter 1. Understanding the acceleration of Artificial Intelligence Chapter 2. The AI Agentic paradigm Chapter 3. AI in Healthcare: a delicate revolution with high stakes Chapter 4. Medical data: fueling innovation in healthcare PART B: REAL-WORLD APPLICATIONS Chapter 5. Revolutionizing diagnosis and medical imaging Chapter 6. Predictive medicine: anticipating to save lives Chapter 7. AI agentic approach to revolutionize personalized care Chapter 8. Connected health: a digital revolution for all Chapter 9. AI serving hospitals Chapter 10. Digital therapies: a new era for mental health Chapter 11. AI and disability: towards greater autonomy PART C: RESPONSIBLE IMPLEMENTATION Chapter 12. Building trust: ethics at the heart of AI in healthcare Chapter 13. Cybersecurity and AI Chapter 14. Emerging technologies and the future of healthcare Chapter 15. The support system: AI powering what happens before and around care CONCLUSION: Together for Tomorrow’s Health