Vaccine Design

Methods and Protocols, Volume 1. Vaccines for Human Diseases

AvSunil Thomas

Häftad, Engelska, 2022

Del i serien Methods in Molecular Biology

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Beskrivning

This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases.

Produktinformation

Utgivningsdatum:2022-12-18
Mått:178 x 254 x 40 mm
Vikt:1 351 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:711
Upplaga:2
Förlag:Springer-Verlag New York Inc.
ISBN:9781071618868

Utforska kategorier

Onkologi inom Medicin
Kemi inom Naturvetenskap och teknik
Samhällsmedicin och preventiv medicin inom Medicin

Innehållsförteckning

Challenges for Vaccinologists in the First Half of the Twenty First Century.- Principles in Immunology for the Design and Development of Vaccines.- Revisiting the Principles of Designing a Vaccine.- Status of COVID-19 Pandemic before the Administration of Vaccine.- mRNA Vaccines to Protect against Diseases.- Artificial Intelligence in Vaccine and Drug Design.- Vaccines Targeting Numerous Coronavirus Antigens, Ensuring Broader Global Population Coverage: Multi-Epitope and Multi-Patch Vaccines.-Use of Micro-computed Tomography to Visualize and Quantify COVID-19 Vaccine Efficiency in Free-breathing Hamsters.- Design of Replication-Competent VSV- and Ervebo-vectored Vaccines against SARS-CoV-2.- CRISPR Engineering of Bacteriophage T4 to Design Vaccines against SARS-CoV-2 and Emerging Pathogens.- Techniques for Developing and Assessing Immune Responses Induced by Synthetic DNA Vaccines for Emerging Infectious Diseases.- Towards Determining the Epitopes of the Structural proteins of SARS-CoV-2.- Development, production and characterization of hepatitis B subviral envelope particles as a third-generation vaccine.- Generation of CpG-Recoded Zika Virus Vaccine Candidates.- Salmonella Uptake into Gut-Associated Lymphoid Tissues: Implications for Targeted Mucosal Vaccine Design and Delivery.- Development of Human Recombinant Leptospirosis Vaccines.- Induction of T-cell Responses by Vaccination of a Streptococcus pneumoniae Whole Cell Vaccine.- Development of a Bacterial Nanoparticle Vaccine against Escherichia coli.- Construction of Novel Live Genetically Modified BCG Vaccine Candidates using Recombineering Tools.- An Update on Tuberculosis Vaccines.- Structure-Based Design of Diagnostics and Vaccines for Lyme Disease.- Development of a SONIX vaccine to protect against ehrlichiosis.- Development of the Anti-Leishmanial Vaccine.- In Silico Design of Recombinant ChimeraT Cell Peptide Epitope Vaccines for Visceral Leishmaniasis.- Pre-clinical Assessment of the Immunogenicity of Experimental Leishmania Vaccines.- Production of Oral Vaccines Based on Retrovirus Virus-like Particles Pseudotyped with Protozoan-Surface Proteins.- A Fast-Track Phenotypic Characterization of Plasmodium falciparum Vaccine Antigens through Lyse-Reseal Erythrocytes Mediated Delivery (LyRED) of RNA Interference for Targeted Translational Repression.- Plasmodium falciparum Antigen Expression in Leishmania Parasite: A Way Forward for Live Attenuated Vaccine Development.- Molecular Characterization of a Vector-based Candidate Antigen using the 3'–RACE and Genome Walking Methods and In Silico Analysis of the Correspondent Protein for Vaccine Design and Development.- In vitro culture of Plasmodium falciparum for the Production of Mature Gametocytes for Performing Standard Membrane Feeding Assay and Infection of Anopheles spp..- Plasmodium berghei Infection in BALB/c Mice Model as an Animal Model for Malaria Disease Research.- Standard membrane feeding assay for malaria transmission studies.- Generation of Tumor Targeted Dendritic Cell Vaccines with Improved Immunogenic and Migratory Phenotype.- Monocytes as a Cellular Vaccine Platform to Induce Anti-Tumor Immunity.- Beyond Sequencing: Prioritizing and Delivering Neoantigens for Cancer Vaccines.- Proteomics for Development of Food Allergy Vaccines.- Estimating Vaccine Potency using Antibody-based Competition Assays.