• Fri frakt över 249 kr
  • •
  • Snabba leveranser
  • •
  • Billiga böcker
Kundservice

Du är på sajten för privatpersoner.

Företag, bibliotek eller offentlig verksamhet?

Du handlar på classic.bokus.com, där alla dina funktioner finns intakta.
Till classic.bokus.com
Bokus logotyp. Gå till startsidan.
  • Erbjudanden
  • Nyheter
  • Student
  • Topplistor
  • Barn & ungdom
  • Bokus Play
  • E-böcker
  • Pocketböcker
  • Spel & pussel

10% rabatt på allt med kod: NYSTART10 →

Sidfot

Mina sidor

    Hjälp

    • Kundservice
    • Vanliga frågor och svar
    • Frakt och leverans
    • Retur vid ångerrätt
    • Reklamera vara
    • Betalning
    • Köpvillkor
    • Allmänna villkor
    • Information om webbplatsens tillgänglighet

    Om Bokus

    • Om oss
    • Pressrum
    • För studenter
    • För företag
    • För bibliotek och offentlig verksamhet
    • För leverantörer
    • Hållbarhet

    Populärt

    • Aktuella erbjudanden
    • Presentkort
    • Studentlitteratur
    • Nya böcker
    • Topplistor
    • Signerade böcker
    • Engelska böcker

    Inspiration

    • Boktips
    • BookTok
    • Populära bokserier
    • Barnbokskaraktärer
    • Populära författare
    Logotyp för Bokus
    Följ oss på Facebook (extern länk)Följ oss på Instagram (extern länk)Följ oss på YouTube (extern länk)Följ oss på TikTok (extern länk)
    bokus @ CookiesAnpassa cookiesIntegritetspolicyKöpvillkor
    Till Citymail hemsida (extern länk)Till Budbee hemsida (extern länk)Till Postnord hemsida (extern länk)Till Schenker hemsida (extern länk)Till Early Bird hemsida (extern länk)Till Walleys hemsida (extern länk)
    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Kemi
    4. Analytisk kemi

    Dried Blood Spots

    Applications and Techniques

    AvWenkui Li,Mike S. Lee

    Inbunden, Engelska, 2014

    Del i serien Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods

    1 556 kr

    Beställningsvara. Skickas inom 5-8 vardagar. Fri frakt över 249 kr.

    Beskrivning

    An informative and comprehensive book on the applications and techniques of dried blood spot samplingDried blood spot (DBS) sampling involves the collection of a small volume of blood, via a simple prick or other means, from a study subject onto a cellulose or polymer paper card, which is followed by drying and transfer to the laboratory for analysis. For many years, this method of blood sample collection has been extensively utilized in some important areas of human healthcare (for example, newborn screening for inherited metabolic disorders and HIV-related epidemiological studies). Because of its advantages over conventional blood, plasma, or serum sample collection, DBS sampling has been valued by the pharmaceutical industry in drug research and development.Dried Blood Spots: Applications and Techniques features contributions from an international team of leading scientists in the field. Their contributions present a unique resource on the history, principles, procedures, methodologies, applications, and emerging technologies related to DBS.Presented in three parts, the book thoroughly examines: Applications of DBS sampling and associated procedures and methodologies in various human healthcare studiesApplications and perspectives of DBS sampling in drug research and development, and therapeutic drug monitoringNew technologies and emerging applications related to DBS sampling and analysisDried Blood Spots: Applications and Techniques is a valuable working guide for researchers, professionals, and students in healthcare, medical science, diagnostics, clinical chemistry, and pharmaceuticals, etc.

    Produktinformation

    • Utgivningsdatum:2014-08-15
    • Mått:218 x 279 x 23 mm
    • Vikt:1 111 g
    • Format:Inbunden
    • Språk:Engelska
    • Serie:Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods
    • Antal sidor:376
    • Förlag:John Wiley & Sons Inc
    • ISBN:9781118054697

    Utforska kategorier

    • Analytisk kemi inom Naturvetenskap och teknik
    • Patologi inom Medicin
    • Kemi inom Naturvetenskap och teknik

    Mer om författaren

    WENKUI LI currently serves as Senior Fellow in the Department of Drug Metabolism & Pharmacokinetics at Novartis Institutes for BioMedical Research, where he focuses on regulated LC-MS/MS bioanalysis for the toxicokinetic and pharmacokinetic assessment of drug candidates. Dr. Li is a member of the editorial board of Biomedical Chromatography.MIKE S. LEE currently serves as a provider of consulting services specializing in pharmaceutical analysis, accelerated drug discovery and development strategies, and analytical technologies. He has delivered many presentations as invited speaker, plenary speaker, and workshops instructor in the areas of drug discovery and development at universities, conferences, and industrial technical centers. He has published numerous papers and books and obtained two U.S. patents.

    Innehållsförteckning

    • PREFACE viiiCONTRIBUTORS xPART I HISTORY, APPLICATIONS, AND HEALTHCARE1 Overview of the History and Applications of Dried Blood Samples 3W. Harry Hannon and Bradford L. Therrell, Jr.2 Dried Blood Spot Cards 16Brad Davin and W. Harry Hannon3 Dried Blood Spot Sample Collection, Storage, and Transportation 21Joanne Mei4 Dried Blood Spot Specimens for Polymerase Chain Reaction in Molecular Diagnostics and Public Health Surveillance 32Chunfu Yang5 Application of Enzyme Immunoassay Methods Using Dried Blood Spot Specimens 40Mireille B. Kalou6 Applications of Dried Blood Spots in Newborn and Metabolic Screening 53Donald H. Chace, Alan R. Spitzer, and Víctor R. De Jesús7 Dried Blood Spots for Use in HIV-Related Epidemiological Studies in Resource-Limited Settings 76Sridhar V. Basavaraju and John P. Pitman8 Use of Dried Blood Spot Samples in HCV-, HBV-, and Influenza-Related Epidemiological Studies 95Harleen Gakhar and Mark Holodniy9 Applications of Dried Blood Spots in General Human Health Studies 114Eleanor Brindle, Kathleen A. O’Connor, and Dean A. Garrett10 Applications of Dried Blood Spots in Environmental Population Studies 130Antonia M. Calafat and Kayoko Kato11 The Use of Dried Blood Spots and Stains in Forensic Science 140Donald H. Chace and Nicholas T. LappasPART II PHARMACEUTICAL APPLICATIONS12 Pharmaceutical Perspectives of Use of Dried Blood Spots 153Christopher Evans and Neil Spooner13 Punching and Extraction Techniques for Dried Blood Spot Sample Analysis 160Philip Wong and Christopher A. James14 Considerations in Development and Validation of LC-MS/MS Method for Quantitative Analysis of Small Molecules in Dried Blood Spot Samples 168Wenkui Li15 Challenges and Experiences with Dried Blood Spot Technology for Method Development and Validation 179Chester L. Bowen and Christopher A. Evans16 Clinical Implications of Dried Blood Spot Assays for Biotherapeutics 188Matthew E. Szapacs and Jonathan R. Kehler17 Potential Role for Dried Blood Spot Sampling and Bioanalysis in Preclinical Studies 195Qin C. Ji and Laura Patrone18 Clinical and Bioanalytical Evaluation of Dried Blood Spot Sampling for Genotyping and Phenotyping of Cytochrome p450 Enzymes in Healthy Volunteers 202Theo de Boer, Izaak den Daas, Jaap Wieling, Johan Wemer, and LingSing Chen19 Application of Dried Blood Spot Sampling in Clinical Pharmacology Trials and Therapeutic Drug Monitoring 216Kenneth Kulmatycki, Wenkui Li, Xiaoying (Lucy) Xu, and Venkateswar Jarugula20 Automation in Dried Blood Spot Sample Collection, Processing, and Analysis for Quantitative Bioanalysis in Pharmaceutical Industry 229Leimin Fan, Katty Wan, Olga Kavetskaia, and Huaiqin Wu21 Beyond Dried Blood Spots—Application of Dried Matrix Spots 235Shane R. NeedhamPART III NEW TECHNOLOGIES AND EMERGING APPLICATIONS22 Direct Analysis of Dried Blood Spot Samples 245Paul Abu-Rabie23 Paper Spray Ionization for Direct Analysis of Dried Blood Spots 298Jiangjiang Liu, Nicholas E. Manicke, R. Graham Cooks, and Zheng Ouyang24 Direct Solvent Extraction and Analysis of Biomarkers in Dried Blood Spots Using a Flow-Through Autosampler 314David S. Millington, Haoyue Zhang, M. Arthur Moseley, J. Will Thompson, and Peter Smith25 Development of Biomarker Assays for Clinical Diagnostics Using a Digital Microfluidics Platform 325David S. Millington, Ramakrishna Sista, Deeksha Bali, Allen E. Eckhardt, and Vamsee Pamula26 Applications and Chemistry of Cellulose Papers for Dried Blood Spots 332Jacquelynn Luckwell, Åke Danielsson, Barry Johnson, Sarah Clegg, Mark Green, and Alan Pierce27 Derivatization Techniques in Dried Blood Spot Analysis 344Ann-Sofie M.E. Ingels, Nele Sadones, Pieter M.M. De Kesel, Willy E. Lambert, and Christophe P. StoveINDEX 355