PROFESSOR BARBARA BAIN, MB BS, FRACP, FRCPath, Professor of Diagnostic Haematology, St Mary's Hospital Campus, Imperial College Faculty of Medicine, Consultant Haematologist, St Mary's Hospital, London, UK

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• Preface viiAbbreviations viii1 The Blood Film and Count 1Blood 1The blood film 1The blood count 17Normal ranges 20How to examine a blood film 222 Assessing Red Cells 29Assessing red cell number and distribution (anaemia polycythaemia rouleaux formation red cell agglutination) 29Assessing red cell size (microcytosis macrocytosis anisocytosis) 32Assessing red cell shape (poikilocytosis) 32Assessing red cell colour (hypochromia hyperchromia anisochromasia polychromasia) 32Detecting red cell inclusions (Pappenheimer bodies basophilic stippling Howell–Jolly bodies) 41The full blood count in red cell assessment 433 Assessing White Cells and Platelets 45Assessing white cell and platelet numbers 45Assessing neutrophil morphology 46Assessing lymphocyte morphology 51Assessing morphology of monocytes eosinophils and basophils 53Assessing platelet morphology 534 Haematological Findings in Health and Disease 55The blood film and count in healthy individuals 55Abnormalities of red cells 56Abnormalities of white cells 775 Emergency Morphology: The Relevance of the Full Blood Count and Blood Film in Acute Illness 97Thrombocytopenia 97Thrombotic microangiopathy and microangiopathic haemolytic anaemia 98Other acute anaemia 100Kidney injury and disease 105Acute hepatic damage and liver failure 107Acute leukaemia 109Bacterial infection and other causes of leucocytosis 109Eosinophilia 113Lymphocytosis 115Malaria 116Neutropenia 119Pancytopenia and leucoerythroblastic blood films 121Neonatal emergencies 1226 Self]assessment 125Index 143

PROFESSOR BARBARA BAIN, MB BS, FRACP, FRCPath, Professor of Diagnostic Haematology, St Mary's Hospital Campus, Imperial College Faculty of Medicine, Consultant Haematologist, St Mary's Hospital, London, UK

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• Preface viiAbbreviations viii1 The Blood Film and Count 1Blood 1The blood film 1The blood count 17Normal ranges 20How to examine a blood film 222 Assessing Red Cells 29Assessing red cell number and distribution (anaemia polycythaemia rouleaux formation red cell agglutination) 29Assessing red cell size (microcytosis macrocytosis anisocytosis) 32Assessing red cell shape (poikilocytosis) 32Assessing red cell colour (hypochromia hyperchromia anisochromasia polychromasia) 32Detecting red cell inclusions (Pappenheimer bodies basophilic stippling Howell–Jolly bodies) 41The full blood count in red cell assessment 433 Assessing White Cells and Platelets 45Assessing white cell and platelet numbers 45Assessing neutrophil morphology 46Assessing lymphocyte morphology 51Assessing morphology of monocytes eosinophils and basophils 53Assessing platelet morphology 534 Haematological Findings in Health and Disease 55The blood film and count in healthy individuals 55Abnormalities of red cells 56Abnormalities of white cells 775 Emergency Morphology: The Relevance of the Full Blood Count and Blood Film in Acute Illness 97Thrombocytopenia 97Thrombotic microangiopathy and microangiopathic haemolytic anaemia 98Other acute anaemia 100Kidney injury and disease 105Acute hepatic damage and liver failure 107Acute leukaemia 109Bacterial infection and other causes of leucocytosis 109Eosinophilia 113Lymphocytosis 115Malaria 116Neutropenia 119Pancytopenia and leucoerythroblastic blood films 121Neonatal emergencies 1226 Self]assessment 125Index 143

PROFESSOR BARBARA BAIN, MB BS, FRACP, FRCPath, Professor of Diagnostic Haematology, St Mary's Hospital Campus, Imperial College Faculty of Medicine, Consultant Haematologist, St Mary's Hospital, London, UK

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• Preface viiAbbreviations viii1 The Blood Film and Count 1Blood 1The blood film 1The blood count 17Normal ranges 20How to examine a blood film 222 Assessing Red Cells 29Assessing red cell number and distribution (anaemia polycythaemia rouleaux formation red cell agglutination) 29Assessing red cell size (microcytosis macrocytosis anisocytosis) 32Assessing red cell shape (poikilocytosis) 32Assessing red cell colour (hypochromia hyperchromia anisochromasia polychromasia) 32Detecting red cell inclusions (Pappenheimer bodies basophilic stippling Howell–Jolly bodies) 41The full blood count in red cell assessment 433 Assessing White Cells and Platelets 45Assessing white cell and platelet numbers 45Assessing neutrophil morphology 46Assessing lymphocyte morphology 51Assessing morphology of monocytes eosinophils and basophils 53Assessing platelet morphology 534 Haematological Findings in Health and Disease 55The blood film and count in healthy individuals 55Abnormalities of red cells 56Abnormalities of white cells 775 Emergency Morphology: The Relevance of the Full Blood Count and Blood Film in Acute Illness 97Thrombocytopenia 97Thrombotic microangiopathy and microangiopathic haemolytic anaemia 98Other acute anaemia 100Kidney injury and disease 105Acute hepatic damage and liver failure 107Acute leukaemia 109Bacterial infection and other causes of leucocytosis 109Eosinophilia 113Lymphocytosis 115Malaria 116Neutropenia 119Pancytopenia and leucoerythroblastic blood films 121Neonatal emergencies 1226 Self]assessment 125Index 143