Mild Cognitive Impairment

Tuokko, Holly A.; Hultsch, David F.

"This valuable volume brings the kind of broad perspective to mild cognitive impairment that has long been needed. Rather than basing conclusions on a single sample or framework, the editors have pulled together articles from leading research groups around the world. This is the kind of comprehensive approach that is needed for developing systematic and valid definitions of MCI and identifying better tools that make it possible to differentiate between benign memory changes in later life and the early signs of pathological processes." - Steven H. Zarit, Department of Human Development and Family Studies, The Pennsylvania State University"This volume provides the most comprehensive overview of mild cognitive impairment currently available. The conceptual and methodological challenges for studying MCI are tackled with rigor, and the complexities of defining the syndrome are not underestimated. This book is certain to become a classic text for those studying or researching cognitive agin, MCI and dementia, and for clinicians seeking an authoritative reference on the clinical manifestations of MCI." - Kaarin J. Anstey, Centre for Mental Health Research, Australian National University"The editors of this book have done a great job. The description of the issues is laid out in a well-written introduction, making the descriptions of the research papers very accessible, even to the less well-informed reader. The conclusion likewise pulled together the various strands, including defining what still needs to be done to further refine the concept of MCI." - Graham A. Jackson, Laverndale Hospital, Scotland. In Dementia, August, 2008

• Part 1. Introduction. H. Tuokko, I. McDowell, An Overview of Mild Cognitive Impairment. Part 2. General Population Research on MCI. C. Fabrigoule, P. Barberger-Gateau, J.-F. Dartigues, The PAQUID Study. K. Palmer, L. Bäckman, B.J. Small, L. Fratiglioni, Cognitive Impairment in Elderly Persons without Dementia: Findings from the Kungsholmen Project. J. Fleming, F.E. Matthews, M. Chatfield, C. Brayne, Population Levels of Mild Cognitive Impairment in England and Wales. A. Collie, P. Maruff, D.G. Darby, C. Masters, J. Currie, The Melbourne Aging Study. Part 3. Specific Samples. R. Wilson, N.T. Aggarwal, D.A. Bennett, Mild Cognitive Impairment in the Religious Orders Study. G. Smith, M. Machulda, K. Kantarci, A Perspective from the Mayo Clinic. M.C. Tierney, Prediction of Probable Alzheimer's Disease: The Sunnybrook Memory Study. H. Wolf, H.-J. Gertz, Studies in the Leipzig Memory Clinic: Contribution to the Concept of Mild Cognitive Impairment. Part 4. Interventions. H. Chertkow, Emerging Pharmacological Therapies for Mild Cognitive Impairment. B. Woods, L. Clare, Cognition-based Therapies and Mild Cognitive Impairment. K. Peters, G. Winocur, Combined Therapies in Mild Cognitive Impairment. Part 5. Summary and Future Directions. H. Tuokko, D.F. Hultsch, The Future of Mild Cognitive Impairment.