As our ideas of the human have come under increasing challenges – from technological change, from medical advances, from the existential threat of climate crisis, from an ideological decentering of the human, amongst many other things – the ''posthuman'' has become an increasingly central topic in the Humanities. Bringing together leading scholars from across the world and a wide range of disciplines, this is the most comprehensive available survey of cutting edge contemporary scholarship on posthumanism in literature, culture and theory.

The Bloomsbury Handbook of Posthumanism explores:

- Central critical concepts and approaches, including transhumanism, new materialism and the Anthropocene
- Ethical perspectives on ecology, race, gender and disability
- Technology, from data and artificial intelligence to medicine and genetics
- A wide range of genres and forms, from literary and science fiction, through film, television and music, to comics, video games and social media.