In the mid-1990s, new treatment options opened a new era of AIDS. This book is a study of the shaping of this new era. Well informed by ethnographic as well as statistical data it reveals the complex and ambiguous processes of change in the field of HIV/AIDS and beyond. The main trail of the investigation leads to the changing conceptions of disease and body, moves to the re-defined roles of patients and physicians, and eventually engages with the wide-ranging shifts the production and diffusion of knowledge that the health care system underwent. In doing so, the book captures the new era of AIDS from multiple perspectives and through the voices of physicians as well as people with HIV, and it offers an accessible and engaging account of the wide-ranging responses it caused. As an original and timely contribution to questions of considerable currency in medicine and the social sciences, the book meets the interests of specialists, professionals, researchers and students alike.