The focus of this special issue of "Molecular and Cellular Biochemistry" is the underlying mechanisms that regulate cardiac growth. The new information provided in the issue can be utilized to design new treatment modalities that will reduce the incidence of cardiac failure, which will improve quality of life in patients with chronic heart disease.

The focus of this special issue of "Molecular and Cellular Biochemistry" is the underlying mechanisms that regulate cardiac growth. The new information provided in the issue can be utilized to design new treatment modalities that will reduce the incidence of cardiac failure, which will improve quality of life in patients with chronic heart disease.