Bioinformatics of Genome Regulation and Structure

Bioinformatics of Genome Regulation and Structure covers: - regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; - large-scale genome analysis and functional annotation; - gene structure detection and prediction; - comparative and evolutionary genomics; - computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure-function organization of genomic DNA, RNA, and proteins; - gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; - data warehousing, knowledge discovery and data mining; and, analysis of basic patterns of genome operation, organization, and evolution. The data presented may be used while solving a wide range of problems, both basic and applied, in various directions of molecular biology, molecular genetics, biotechnology, pharmacogenetics, pharmacology, and adjacent fields of medicine, veterinary, and agrobiology.