Topical Nail Products and Ungual Drug Delivery

AvHoward I. Maibach,S Narasimha Murthy

E-bok
PDF, Engelska, 2012

1 229 kr

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Beskrivning

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.

Topics Include

  • Nail anatomy, physiology, diseases, and treatment
  • Permeability of the nail plate
  • Topical nail formulations
  • Approaches to enhance ungual and trans-ungual drug delivery
  • In vitro and in vivo models to evaluate topical nail formulations
  • Nail sampling techniques
  • Bioengineering of the nail
  • Trans-ungual iontophoresis
  • Pharmacokinetics of drugs in the nail apparatus
  • Onychopharmacokinetics: proposed model insight
  • Photodynamic therapy of nail diseases
  • The nail as a surrogate for investigating drug use

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