Systems Biology for Signaling Networks

Inbunden, Engelska, 2010

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Beskrivning

Highlighting key research findings in a volatile, evolving field, this book presents pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data.

Produktinformation

Utgivningsdatum:2010-08-18
Mått:155 x 235 x 52 mm
Vikt:1 705 g
Format:Inbunden
Språk:Engelska
Serie:Systems Biology
Antal sidor:908
Upplaga:2010
Förlag:Springer-Verlag New York Inc.
ISBN:9781441957962

Utforska kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Concepts.- Systems Biology Approaches: Solving New Puzzles in a Symphonic Manner.- Current Progress in Static and Dynamic Modeling of Biological Networks.- Getting Started in Biological Pathway Construction.- From Microarray to Biology.- Modeling and Reconstruction.- Computational Procedures for Model Identification.- Assembly of Logic-Based Diagrams of Biological Pathways.- Automating Mathematical Modeling of Biochemical Reaction Networks.- Strategies to Investigate Signal Transduction Pathways with Mathematical Modelling.- Inferring Transcriptional Regulatory Network.- Finding Functional Modules.- Modeling the Dynamics of Biological Networks from Time Course Data.- Decision Making in Cells.- Robustness of Neural Network Models.- Functional Modules in Protein–Protein Interaction Networks.- Mixture Model on Graphs: A Probabilistic Model for Network-Based Analysis of Proteomic Data.- Integration of Network Information for Protein Function Prediction.- Applications for Signaling Networks.- Cellular-Level Gene Regulatory Networks: Their Derivation and Properties.- Tyrosine-Phosphoproteome Dynamics.- Systems Biology of the MAPK1,2 Network.- Pathway Crosstalk Network.- Crosstalk Between Mitogen-Activated Protein Kinase and Phosphoinositide-3 Kinase Signaling Pathways in Development and Disease.- Systems-Level Analyses of the Mammalian Innate Immune Response.- Molecular Basis of Protective Anti-Inflammatory Signalling by Cyclic AMP in the Vascular Endothelium.- Construction of Cancer-Perturbed Protein–Protein Interaction Network of Apoptosis for Drug Target Discovery.- Transcriptional Changes in Alzheimer’s Disease.- Pathogenesis of Obesity-Related Chronic Liver Diseases as the Study Case for the Systems Biology.- The Evolving Transcriptome of Head and Neck SquamousCell Carcinoma.- Peptide Microarrays for a Network Analysis of Changes in Molecular Interactions in Cellular Signalling.- Tools for Systems Biology.- A Primer on Modular Mass-Action Modelling with CellML.- FERN – Stochastic Simulation and Evaluation of Reaction Networks.- Programming Biology in BlenX.- Discrete Modelling: Petri Net and Logical Approaches.- ProteoLens: A Database-Driven Visual Data Mining Tool for Network Biology.- MADNet: A Web Server for Contextual Analysis and Visualization of High-Throughput Experiments.- Erratum to: Functional Modules in Protein–Protein Interaction Networks.