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Beskrivning
This book is meant to integrate the emerging body of information that has been accumulating, revealing the interactive nature of the brain's two major neural cell types, neurons and glia, in brain function.
1. The glial-neuronal interactions and signaling: an introduction.- 2. Gene function in glial-neuronal interactions.- 3. Structural association of glia with the various compartments of neurons.- 4. Morphological plasticity of astroglial/neuronal interactions: functional implications.- 5. Astroglia as a modulation interface between meninges and neurons.- 6. Expression and possible functions of glutamate and GABA receptors in glial cells from the hippocampus.- 7. Ion channels in astrocytes.- 8. Specialized channels in astrocytes.- 9. Glutamate uptake by astroglia.- 10. pH regulation and acid/base-mediated transport in glial cells.- 11. Glial-neuronal interactions and brain energy metabolism.- 12. Calcium signaling in glia.- 13. Astrocyte gap junctions and glutamate-induced neurotoxicity.- 14. Mechanism and significance of astrocytic Ca2+ signaling.- 15. Glutamate-mediated bi-directional signaling between neurons and astrocytes.- 16. The regulated release of transmitters from astrocytes.- 17. Role of astrocytes in the formation, maturation and maintenance of synapses.
