Bioinformatics and Drug Discovery

Häftad, Engelska, 2016

Del i serien Methods in Molecular Biology

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Beskrivning

The second edition of Bioinformatics and Drug Discovery has been completely updated to include topics that range from new technologies in target identification, genomic analysis, cheminformatics, protein analysis, and network or pathway analysis.

Produktinformation

Utgivningsdatum:2016-08-23
Mått:178 x 254 x 21 mm
Vikt:728 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:374
Upplaga:2
Förlag:Humana Press Inc.
ISBN:9781493959297

Utforska kategorier

Biovetenskap inom Naturvetenskap och teknik
Apotek och farmaceuter inom Medicin

Innehållsförteckning

Cell Perturbation Screens for Target Identification by RNAi.-Using Functional Genomics to Identify Drug Targets: a Dupuytren’s Disease Example.-Functional Characterization of Human Genes from Exon Expression and RNA Interference Results.-Barcode Sequencing for Understanding Drug-gene Interactions.-High-Throughput Sequencing of the Methylome Using Two-Base Encoding.-Applications and Limitations of In Silico Models In Drug Discovery.-Compound Collection Preparation for Virtual Screening.-Mapping Between Databases of Compounds and Protein Targest.-Predictive Cheminformatics in Drug Discovery: Statistical Modeling for Analysis of Micro-Array and Gene Expression Data.-Advances in Nuclear Magnetic Resonance for Drug Discovery.-Human ABC Transporter ABCG2 in Cancer Chemotherapy: Drug Molecular Design to Circumvent Multidrug Resistance.-Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection.-Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis.-Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes.-Integration of Multiple Ubiquitin Signals in Proteasome Regulation.