Metals in the Brain

Measurement and Imaging

AvAnthony R. White

Häftad, Engelska, 2018

Del i serien Neuromethods

1 863 kr

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Beskrivning

The chapters in this book discuss the use of fluorescent metal probes, synchrotron-based X-ray microscopy, ICP-MS, laser ablation-ICP-MS, laser-based tissue microdissection, MRI image analysis, fractionation of cell tissue samples for metal analysis, and metal treatment of cells.

Produktinformation

Utgivningsdatum:2018-07-20
Mått:178 x 254 x 16 mm
Vikt:540 g
Format:Häftad
Språk:Engelska
Serie:Neuromethods
Antal sidor:270
Förlag:Humana Press Inc.
ISBN:9781493983384

Utforska kategorier

Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Introduction and Overview.- X-Ray Microscopy for Detection of Metals in the Brain.- Imaging Metals in the Brain by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry.- Fluorescent Probes for the Analysis of Labile Metals in the Brain Cells.- Probing Biological Trace Metals with Fluorescent Indicators.- Microdissection of Brain Tissue to Resolve the Comparative Dissemination of Metal Concentrations in Neurodegenerative Diseases, Focusing on Manganese.- Analysis of Trace Elements and Metalloproteins in Fractionated Human Brain Samples using Size Exclusion Inductively Couples Mass Spectrometry.- Size-Fractionation of Metal Species from Serum Samples for Studying Element Biodistribution in Alzheimer’s Disease.- Lead Uptake and Localization in Glial Cell Cultures.- Evaluating Iron Flux in the Brain.- Current Methods used to Probe and Quantify Intracellular Total and Free Zn(II) Dynamics, and Subcellular Distribution in Cultured Neurons.- Monitoring Intracellular Zn2+ using Fluorescent Sensors: Facts and Artifacts.- Measuring Changes in Brain Manganese or Iron using Magnetic Resonance Imaging (MRI).- Treatment and Measurement of Metals in Brain Cell Cultures.