Neuroproteomics

Methods and Protocols

AvFiras H. Kobeissy,Stanley M. Stevens, Jr.

Häftad, Engelska, 2018

Del i serien Methods in Molecular Biology

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Beskrivning

This new edition provides updated and novel protocols of neuroproteomics methods that encompass both global-scale as well as targeted and specialized topics, which are timely additions for the molecular and phenotypic analysis of the central nervous system and CNS-related disorders.

Produktinformation

Utgivningsdatum:2018-08-08
Mått:178 x 254 x 24 mm
Vikt:829 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:424
Upplaga:2
Förlag:Humana Press Inc.
ISBN:9781493983490

Utforska kategorier

Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Neuroproteomics Studies: Challenges and Updates.- Progress and Potential of Imaging Mass Spectrometry Applied to Biomarker Discovery.- Biofluid Proteomics and Biomarkers in Traumatic Brain Injury.- Degradomics in Neurotrauma: Profiling Traumatic Brain Injury.- Evolving Relevance of Neuroproteomics in Alzheimer’s Disease.- Genome to Phenome: A Systems Biology Approach to PTSD Using an Animal Model.- Photoaffinity Labeling of Pentameric Ligand-Gated Ion Channels to Identify: A Proteomic Approach to Identify Allosteric Ligand Binding Sites.- Quantitative Phosphoproteomic Analysis of Brain Tissues.- Glycoproteins Enrichment and LC-MS/MS Glycoproteomics in Central Nervous System Applications.- A Novel 2-DE-Based Proteomic Analysis to Identify Multiple Substrates for Specific Protease in Neuronal Cells.- Neuroproteomic Profiling of Cerebrospinal Fluid (CSF) by Multiplexed Affinity Arrays.- Isolation and Proteomic Analysis of Microvesicles and Exosomes from HT22 Cells and Primary Neurons.- Combined MALDI Mass Spectrometry Imaging and Parafilm-Assisted Microdissection-Based LC-MS/MS Workflows in the Study of the Brain.- De Novo and Uninterrupted SILAC Labeling of Primary Microglia.- Spike-In SILAC Approach for Proteomic Analysis of Ex Vivo Microglia.- A Proteomic Evaluation of Sympathetic Activity Biomarkers of the Hypothalamus-Pituitary-Adrenal Axis by Western Blotting Technique Following Experimental Traumatic Brain Injury.- Efficient and Accurate Algorithm for Cleaved Fragments Prediction (CFPA) in Protein Sequences Dataset Based on Consensus and Its Variants: A Novel Degradomics Prediction Application.- Effect of Second-Hand Tobacco Smoke on the Nitration of Brain Proteins: A Systems Biology & Bioinformatics Approach.- An Advanced Omic Approach to Identify Co-Regulated Clusters and Transcription Regulation Network with AGCT and SHOE Methods.- AutoDock and AutoDockTools for Protein-Ligand Docking: Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1(BACE1) as a Case Study.- An Integration of Decision Tree and Visual Analysis to Analyze Intracranial Pressure.