HLA Typing

Methods and Protocols

AvSebastian Boegel

Häftad, Engelska, 2019

Del i serien Methods in Molecular Biology

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Beskrivning

This volume explores the rapidly evolving field of HLA typing and its use in both the laboratory setting and in silico methods.

Produktinformation

Utgivningsdatum:2019-07-25
Mått:178 x 254 x 16 mm
Vikt:645 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:287
Förlag:Humana Press Inc.
ISBN:9781493993215

Utforska kategorier

Onkologi inom Medicin
Hematologi inom Medicin

Innehållsförteckning

The Past, Present, and Future of HLA Typing in Transplantation.- Role of Human Leukocyte Antigens (HLA) in Autoimmune Diseases.- The IPD Databases: Cataloguing and Understanding Allele Variants.- Allele Frequency Net Database.- High Resolution HLA-Typing by Next Generation Sequencing of Randomly Fragmented Target DNA.- High-Throughput Contiguous Full-Length Next Generation Sequencing of HLA Class I and II Genes from 96 Donors in a Single MiSeq Run.- Application of High-Throughput Next Generation Sequencing for HLA Typing on Buccal Extracted DNA.- Super High Resolution for Single Molecule-Sequence-Based Typing of Classical HLA loci using Ion Torrent PGM.- High Resolution Full-Length HLA Typing Method using Third Generation (Pac-Bio SMRT) Sequencing Technology.- Full-Length HLA Class I Genotyping with the MinION Nanopore Sequencer.- Imputation-Based HLA Typing with SNPs in GWAS Studies.- In Silico Typing of Classical and Non-Classical HLA Alleles from Standard RNA-Seq Reads.- PHLAT: Inference of High Resolution HLA Types from RNA and Whole Exome Sequencing.- Using Exome and Amplicon-Based Sequencing Data for High-Resolution HLA Typing with ATHLATES.- HLA Typing from Short-Read Sequencing Data with OptiType.- Comprehensive HLA Typing from a Current Allele Database using Next Generation Sequencing Data.- Accurate Assembly and Typing of HLA using a Graph-Guided Assembler Kourami.- AmpliSAS and AmpliHLA: Web Server Tools for MHC Typing of Non-Model Species and Human using NGS Data.- HLA Haplotype Frequency Estimation from Real-Life Data with the Hapl-o-Mat Software.