The Structured Clinical Interview for DSM-5 Disorders—Clinician Version (SCID-5-CV) guides the clinician step-by-step through the DSM-5 diagnostic process. Interview questions are provided conveniently along each corresponding DSM-5 criterion, which aids in rating each as either present or absent. A unique and valuable tool, the SCID-5-CV covers the DSM-5 diagnoses most commonly seen in clinical settings. The User's Guide for the SCID-5-CV provides comprehensive instructions on how to use the SCID-5-CV effectively and accurately. It not only describes the rationale, structure, conventions, and usage of the SCID-5-CV, but also discusses in detail how to interpret and apply the specific DSM-5 criteria for each of the disorders included in the SCID-5-CV. A number of sample role-play and homework cases are also included to help clinicians learn how to use the SCID-5-CV. Together with the SCID-5-CV, the User's Guide for the SCID-5-CV will prove invaluable to clinicians, researchers, interviewers, and students in the mental health professions who seek to integrate time-tested interview questions corresponding to the DSM-5 criteria into their DSM-5 diagnostic assessment process.