In the year 2008 the new "e;Journal of Pain Management"e; was begun under the auspices of the National Institute of Child Health and Human Development in Israel in collaboration with Nova Science Publishers in New York with the hopes of facilitating an outlet for peer-reviewed papers in the areas of pain and pain management from a holistic, practical, and clinical point of view. This yearbook for 2008 contains selected research published from the "e;Journal of Pain Management"e; by leading researchers from all over the world.