Bokus
Jacqueline Boultwood, Carrie Fidler - Molecular Analysis of Cancer, Häftad

Häftad, Engelska, 2011

Molecular Analysis of Cancer

Av Jacqueline Boultwood, Carrie Fidler

Del i serien Methods in Molecular Medicine

1225 kr

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Beskrivning
Leading researchers describe in step-by-step detail their best state-of-the art molecular techniques for elucidating the biochemical processes associated with human cancer. Among the techniques presented for identifying chromosomal rearrangements are fluorescent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), microsatellite analysis, PCR and RT-PCR, and DNA fingerprinting. Additional methods include SSCP, DGGE, the nonisotopic RNase cleavage assay, and the protein truncation assay and DNA sequencing for identifying mutations.
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"The book covers a broad range of topics and provides many useful suggestions as well as practical guidance for the lab researcher." -Doody's Health Sciences Book Review Journal "This book gives a good overview of currently available methods for investigating molecular changes in cancers,...it illustrates how you, the cancer researcher, can apply the methods to your oncology problem...The most enjoyable chapters also illustrate the methods with real results, so that you can see what to expect, e.g. chapter 3 on spectral karyotyping...a useful addition in any oncology research laboratory, because it presents this large variety of methods in a compact format, so that someone waiting to try a new approach could easily dip into the book to see what is available." - Molecular Biotechnology "Comprehensive and state-of-the-art, Molecular Analysis of Cancer not only offers today's researcher a deeper understanding of cancer's molecular pathogenesis, but also provides a detailed examination of each of the major methodologies needed to detect and analyze its associated genetic abnormalities." - Clinical Laboratory "...good integration between preliminary explanations of techniques and practical instructions with easily available tables or figures." - Proteomics

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