COMPARATIVE PHYSIOLOGY, NATURAL ANIMAL MODELS AND CLINICAL MEDICINE: INSIGHTS INTO CLINICAL MEDICINE FROM ANIMAL ADAPTATIONS

"This is an interesting and important book ... A few of these questions about natural models for disease have been raised before by comparative physiologists, but they have largely been ignored by those involved in medical research. Dr Singer hopes that a presentation by a clinician will correct this situation. I sincerely hope that he is correct for I agree with his basic thesis."Professor Emeritus William H DantzlerUniversity of Arizona"Michael Singer has produced a marvellous volume of thought provoking observations ... This volume presents a tour de force of integrative and comparative physiology to consider the possible answers to such questions ... For many reasons, I cannot recommend this splendid book highly enough."Troels RingAalborg Hospital, Denmark"The style is easily readable, with a logical progression from a clinical setting in the Introduction, through a number of common disease entities ... There is a satisfying combination of science and art, and a call for further research in each area ... The book is suitable for medical professionals of all levels of training and interests, from the Basic Scientist in the laboratory to the Clinician at the bedside."Professor A R MortonQueen's University, Ontario

• Introduction; Diabetes Mellitus; Chronic Renal Failure; Atherosclerotic Vascular Disease; Disuse Osteoporosis and Disuse Muscle Atrophy; Ammonia Toxicity; Hypoxia/Ischemia; Epilogue.