Professor Lakshmi Nagarajan is Consultant Neurologist/Epileptologist and Head of the Department of Neurology at the Princess Margaret Hospital for Children, Perth, Western Australia. She also runs the Comprehensive Epilepsy Programme for Children and Adolescents in Western Australia. Her research interests include neonatal seizures, childhood epilepsy, paediatric neurology and clinical neurophysiology. Prof Nagarajan is a member of the Board of Directors of the International Child Neurology Association and the Australian New Zealand Child Neurology Society. She has published close to 50 papers in peer reviewed journals.

• AUTHORS' APPOINTMENTS viiFOREWORD xPREFACE xiiACKNOWLEDGEMENTS xiii1. DEVELOPMENT OF THE NEONATAL CEREBRAL CORTEX 1Soumya Ghosh2. THE ROLE OF THE VIDEO EEG IN NEONATES WITH SEIZURES 12Lakshmi Nagarajan and Soumya Ghosh3. RECORDING A VIDEO-EEG STUDY IN A NEONATE 30Linda Palumbo and Lakshmi Nagarajan4. THE ROLE OF AMPLITUDE-INTEGRATED EEG IN THE MANAGEMENT OF NEONATAL SEIZURES 40Lena Hellström-Westas, Ingmar Rosén and Linda S. de Vries5. ADVANCES IN NEUROPHYSIOLOGY AND NEONATAL SEIZURES: AUTOMATED SEIZURE DETECTION 56Nathan J. Stevenson and Geraldine B. Boylan6. NEUROIMAGING IN NEONATAL SEIZURES 76Camilo Jaimes, Christos Papadelis and P. Ellen Grant7. NEONATAL EPILEPSIES AND EPILEPTIC ENCEPHALOPATHIES 100Maria Roberta Cilio8. CLINICAL APPROACH TO A NEONATE WITH SEIZURES 114Shripada Rao, Barry Lewis, Soumya Ghosh and Lakshmi Nagarajan9. TREATMENT OF NEONATAL SEIZURES 128Lakshmi Nagarajan10. PREDICTORS OF NEURODEVELOPMENTAL OUTCOME IN INFANTS WITH NEONATAL SEIZURES 146Lakshmi Nagarajan, Andrea Poretti, Thierry A G M Huisman and Soumya Ghosh11. NEURODEVELOPMENTAL OUTCOMES OF NEONATES WITH SEIZURES 163Jarred Garfinkle and Michael I Shevell12. NEUROPROTECTIVE STRATEGIES FOR NEONATES WITH SEIZURES 172Shilpa D. Kadam, Xiaohe Yu and Michael V. JohnstonINDEX 193