Mechanisms of Drug Resistance in Cancer Therapy

Inbunden, Engelska, 2019

Del 249 i serien Handbook of Experimental Pharmacology

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Beskrivning

A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments.

Produktinformation

Utgivningsdatum:2019-01-23
Mått:155 x 235 x 23 mm
Vikt:629 g
Format:Inbunden
Språk:Engelska
Serie:Handbook of Experimental Pharmacology
Antal sidor:297
Förlag:Springer Nature Switzerland AG
ISBN:9783030105068

Utforska kategorier

Onkologi inom Medicin
Farmakologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin

Innehållsförteckning

1. Molecular and Pharmacological Mechanisms of Drug Resistance: An Evolving Paradigm.- 2. Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival.- 3. Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies.- 4. Mechanisms of Resistance to Target Therapies in Non-small Cell Lung Cancer.- 5. Mechanisms of Drug Resistance in Melanoma.- 6.Mechanisms of Resistance to Immune Checkpoint Antibodies.- 7. Immunotolerance as a Mechanism of Resistance to Targeted Therapies in Melanoma.- 8. Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Metastatic Colorectal Cancer.- 9. Targeting DNA repair.- 10.Resistance to Hormonal Therapy in Prostate Cancer.- 11. Mechanism of Resistance in Gastrointestinal Stromal Tumors.- 12. Mechanisms of Resistance to Targeted Therapies in Chronic Lymphocytic Leukemia.- 13. Mechanisms of Resistance to Targeted Therapies in Chronic Myeloid Leukemia.- 14. Mechanisms of Resistance in Multiple Myeloma.- 15. Cancer Evolution as the New Frontier of Precision.