Handbook of Experimental Pharmacology – serie
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469 produkter
Delta Opioid Receptor Pharmacology and Therapeutic Applications
Häftad, 2018
1299 kr
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This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds …
Voltage-gated Sodium Channels: Structure, Function and Channelopathies
Häftad, 2019
1692 kr
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This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their …
Targeting Trafficking in Drug Development
Av Alfredo Ulloa-Aguirre, Ya-Xiong Tao
Häftad, 2019
2341 kr
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Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are …
Mechanisms of Drug Resistance in Cancer Therapy
Av Mario Mandalà, Emanuela Romano
Inbunden, 2019
1692 kr
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A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments. It …
Brown Adipose Tissue
Av Alexander Pfeifer, Martin Klingenspor m. fl.
Inbunden, 2019
2253 kr
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The main focus of this book is on brown adipose tissue and its metabolic function. The book provides a timely update on the latest research and shows where the field is heading. Brown adipose tissue (BAT) dissipates energy and has received considerable attention in the last few years, having been …
New Psychoactive Substances
Pharmacology, Clinical, Forensic and Analytical Toxicology
Av Hans H. Maurer, Simon D. Brandt
Inbunden, 2019
1917 kr
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This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly developing phenomenon.
Antidepressants
From Biogenic Amines to New Mechanisms of Action
Av Matthew Macaluso, Sheldon H. Preskorn
Inbunden, 2019
1692 kr
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This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.
Sleep-Wake Neurobiology and Pharmacology
Av Hans-Peter Landolt, Derk-Jan Dijk
Inbunden, 2019
1692 kr
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This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug …
Nociceptin/Orphanin FQ Peptide Receptor
Av Mei-Chuan Ko, Girolamo Caló
Inbunden, 2019
1692 kr
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The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for …
Nociceptin/Orphanin FQ Peptide Receptor
Av Mei-Chuan Ko, Girolamo Caló
Häftad, 2020
1692 kr
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The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for …
Calcitonin Gene-Related Peptide (CGRP) Mechanisms
Focus on Migraine
Av Susan D. Brain, Pierangelo Geppetti
Inbunden, 2019
1467 kr
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This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various …
Calcitonin Gene-Related Peptide (CGRP) Mechanisms
Focus on Migraine
Av Susan D. Brain, Pierangelo Geppetti
Häftad, 2020
1128 kr
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This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various …
Bile Acids and Their Receptors
Av Stefano Fiorucci, Eleonora Distrutti
Inbunden, 2019
1692 kr
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This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to …
Bile Acids and Their Receptors
Av Stefano Fiorucci, Eleonora Distrutti
Häftad, 2020
1243 kr
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This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to …
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Av Anton Bespalov, Martin C. Michel m. fl.
Inbunden, 2020
569 kr
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This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Av Anton Bespalov, Martin C. Michel m. fl.
Häftad, 2020
569 kr
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This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Lipid Signaling in Human Diseases
Av Julian Gomez-Cambronero, Michael A. Frohman
Inbunden, 2020
1692 kr
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Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases, sphingosine kinases, and their …
Lipid Signaling in Human Diseases
Av Julian Gomez-Cambronero, Michael A. Frohman
Häftad, 2021
1692 kr
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Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases, sphingosine kinases, and their …
Substance Use Disorders
From Etiology to Treatment
Av Michael A. Nader, Yasmin L. Hurd
Inbunden, 2020
1692 kr
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The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use …
Substance Use Disorders
From Etiology to Treatment
Av Michael A. Nader, Yasmin L. Hurd
Häftad, 2021
1692 kr
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The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use …
Concepts and Principles of Pharmacology
100 Years of the Handbook of Experimental Pharmacology
Av James E. Barrett, Clive P. Page m. fl.
Inbunden, 2020
1917 kr
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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. …
Pediatric Pharmacotherapy
Av Wieland Kiess, Matthias Schwab m. fl.
Inbunden, 2020
1692 kr
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This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned …
Pediatric Pharmacotherapy
Av Wieland Kiess, Matthias Schwab m. fl.
Häftad, 2021
1692 kr
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This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned …
Bone Regulators and Osteoporosis Therapy
Inbunden, 2020
1692 kr
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This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, …
Bone Regulators and Osteoporosis Therapy
Häftad, 2021
1692 kr
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This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, …
Botulinum Toxin Therapy
Av Scott M. Whitcup, Mark Hallett
Inbunden, 2021
1692 kr
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In a rapidly progressing field, Botulinum Toxin Therapy provides both clinicians and basic researchers with the latest science on the structure and function of botulinum toxins and the use of these toxins to treat a wide variety of diseases. Part 1 of the book reviews the basic science of botulinum …
Botulinum Toxin Therapy
Av Scott M. Whitcup, Mark Hallett
Häftad, 2022
1692 kr
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In a rapidly progressing field, Botulinum Toxin Therapy provides both clinicians and basic researchers with the latest science on the structure and function of botulinum toxins and the use of these toxins to treat a wide variety of diseases. Part 1 of the book reviews the basic science of botulinum …
Reactive Oxygen Species
Network Pharmacology and Therapeutic Applications
Av Harald H. H. W. Schmidt, Pietro Ghezzi m. fl.
Inbunden, 2021
2253 kr
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Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and …
Reactive Oxygen Species
Network Pharmacology and Therapeutic Applications
Av Harald H. H. W. Schmidt, Pietro Ghezzi m. fl.
Häftad, 2022
2253 kr
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Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and …
Organotypic Models in Drug Development
Av Monika Schäfer-Korting, Silvya Stuchi Maria-Engler m. fl.
Inbunden, 2021
2253 kr
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This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major …
