Delta Opioid Receptor Pharmacology and Therapeutic Applications

Häftad, Engelska, 2018

Del 247 i serien Handbook of Experimental Pharmacology

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Beskrivning

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system.

Produktinformation

Utgivningsdatum:2018-12-20
Mått:155 x 235 x 20 mm
Vikt:540 g
Format:Häftad
Språk:Engelska
Serie:Handbook of Experimental Pharmacology
Antal sidor:348
Förlag:Springer Nature Switzerland AG
ISBN:9783030069803

Utforska kategorier

Fysiologi inom Medicin
Farmakologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Part 1. DOPR Ligands.- 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept.- 2. Multifunctional Opioid Ligands.- 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins.- Part 2. DOPR Signaling.- 4. Ligand-Directed Signaling at the Delta Opioid Receptor.- 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons.- 6. Evidence and Function Relevance of Native DOR–MOR Heteromers.- Part 3. DOPR and Disease.- 8. The Delta Opioid Receptor in Pain Control.- 9. Delta Opioid Receptors and Modulation of Mood and Emotion.- 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors.- 11. Delta Opioid Receptors: Learning and Motivation.- 12. Delta Opioid Pharmacology in Parkinson’s Disease.- 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders.-14. Delta Opioid Receptors and Cardioprotection.- 15. The Roles of Opioid Receptors in Cutaneous Wound Healing.