Heart of the Matter

Cesare Terracciano is a Professor of Cardiac Electrophysiology, Director of the BSc course in Cardiovascular Sciences at Imperial College London, and a PI of the British Heart Foundation Cardiovascular Regenerative Centre, UK.Samuel Guymer is a medical student at St. George’s, University of London and graduate of the Cardiovascular Sciences, BSc programme at Imperial College London.

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• Anatomy of the Heart and Coronary Vasculature.- Early Mechanisms of Cardiac Development.- Later Mechanisms of Cardiac Development.-  Myocardial Microstructure and Contractile Apparatus.- An Introduction to the Cardiac Action Potentials.- Cardiac Excitation-Contraction Coupling.- Conduction in Normal and Diseased Myocardium.- Cell-Based Tachyarrhythmias and Bradyarrhythmias.- The Scientific Rationale of Artificial Pacing.- Cardiac Contractility.- The Scientific Basis of Heart Failure.- Molecular and Cellular Basis of Cardiomyopathies.- Substrate Remodelling Changes in Heart Failure.- Developments in Heart Failure: Mechanical Unloading with LVADs, Exosomes, and MicroRNAs.- Pharmacological Targets of Hypertension.- The Coagulation Cascade and its Therapeutic Modulation.- Cellular and Molecular Mechanisms of Atherosclerosis.- Molecular and Cellular Mechanisms of Angiogenesis.- Endothelial Function in Normal and Diseased Vessels.