Human Population Genomics

Kirk E. Lohmueller is an Associate Professor in the Department of Ecology and Evolutionary Biology as well as Human Genetics at UCLA. He received his PhD from Cornell University in 2010 and then was a Miller Fellow at UC Berkeley till 2013 when he joined the faculty at UCLA. Dr. Lohmueller is a population geneticist who studies a wide range of organisms, including humans, mice, dogs, wolves, foxes, birds, sea otters, and plants. A major focus of his research is understanding how deleterious mutations impact genomes and complex traits. He has received several awards including a Sloan Research Fellowship, Searle Scholar Award, and the Hellman Faculty Fellowship. His research has been supported by the National Institutes of Health, National Science Foundation, and National Institute of Justice.Rasmus Nielsen is a Professor of computational biology in the Department of Integrative Biology and the Department of Statistics at the UC Berkeley, a position he has held since 2008.  He obtained his PhD from UC Berkeley in 1998, did a two-year postdoc at Harvard University 1998-2000, was an Assistant Professor at Cornell University 2000-2004 and has also been a Professor at University of Copenhagen since 2004.  His work focuses on statistical and computational methods in genetics, including methods for elucidating human history using genomic data. He has received multiple fellowships and awards for his work including a Fulbright fellowship, a Sloan Research Fellowship, the AAAS Newcomb Clevealand Price, and the Villum Kann Rasmussen Annual Award. He has published more than 300 peer reviewed publications which have been cited by other researchers more than 75,000 times.

“This book is likely to be most useful to PhD students in the early stages of their graduate degree … . By reading this edited volume, researchers will feel empowered and be able to interpret complex human genomic datasets. … Human Population Genomics: Introduction to Essential Concepts and Applications would be a valuable addition to the bookshelf of any research group that studies this topic.” (Joseph Lachance, The Quarterly Review of Biology, Vol. 97 (3), September, 2022)

• - Part I Population Genetic Theory. - Coalescent Models. - Linkage Disequilibrium. - Analysis of Population Structure. - Types of Natural Selection and Tests of Selection. - Part II Association Studies and Medical Genetics. - Methods for Association Studies. - Identity by Descent in the Mapping of Genetic Traits. - What Have We Learned from GWAS?. - Part III Human Evolutionary Population Genetics. - Inferring Human Demographic History from Genetic Data. - Natural Selection, Genetic Variation, and Human Diversity.