This book presents the proceedings of the 2nd International Congress on Innovation and Research—A Driving Force for Socio-Econo-Technological Development (CI3 2021). CI3 was held on September 1–3, 2021. It was organized by the Instituto Tecnológico Superior Rumiñahui and GDEON, in co-organization with Higher Institutes: Bolivariano de Tecnología, Central Técnico, Espíritu Santo, José Chiriboga Grijalva, ISMAC, Policía Nacional del Ecuador Vida Nueva; and sponsored by the Universidad Nacional Mayor de San Marcos (Peru), Universidade Federal de Goiás (Brazil) and City University of New York (United States). CI3 aims to disseminate the research project results that are being carried out in different Higher Education Institutions, research centers, and the business sector.