This book constitutes the refereed proceedings of the 6th IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2022, held in Vienna, Austria during August 2022.

The 23 full papers presented were carefully reviewed and selected from 45 submissions. The papers are covering a wide range from integrative machine learning approach, considering the importance of data science and visualization for the algorithmic pipeline with a strong emphasis on privacy, data protection, safety and security.

This book constitutes the refereed proceedings of the 6th IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2022, held in Vienna, Austria during August 2022.

The 23 full papers presented were carefully reviewed and selected from 45 submissions. The papers are covering a wide range from integrative machine learning approach, considering the importance of data science and visualization for the algorithmic pipeline with a strong emphasis on privacy, data protection, safety and security.

This book constitutes the refereed proceedings of the 6th IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2022, held in Vienna, Austria during August 2022.

The 23 full papers presented were carefully reviewed and selected from 45 submissions. The papers are covering a wide range from integrative machine learning approach, considering the importance of data science and visualization for the algorithmic pipeline with a strong emphasis on privacy, data protection, safety and security.