This book constitutes the refereed proceedings of the 5th IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2021, held in virtually in August 2021.

The 20 full papers and 2 short papers presented were carefully reviewed and selected from 48 submissions. The cross-domain integration and appraisal of different fields provides an atmosphere to foster different perspectives and opinions; it will offer a platform for novel ideas and a fresh look on the methodologies to put these ideas into business for the benefit of humanity.

This book constitutes the refereed proceedings of the 5th IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2021, held in virtually in August 2021.

The 20 full papers and 2 short papers presented were carefully reviewed and selected from 48 submissions. The cross-domain integration and appraisal of different fields provides an atmosphere to foster different perspectives and opinions; it will offer a platform for novel ideas and a fresh look on the methodologies to put these ideas into business for the benefit of humanity.

This book constitutes the refereed proceedings of the 5th IFIP TC 5, TC 12, WG 8.4, WG 8.9, WG 12.9 International Cross-Domain Conference, CD-MAKE 2021, held in virtually in August 2021.

The 20 full papers and 2 short papers presented were carefully reviewed and selected from 48 submissions. The cross-domain integration and appraisal of different fields provides an atmosphere to foster different perspectives and opinions; it will offer a platform for novel ideas and a fresh look on the methodologies to put these ideas into business for the benefit of humanity.