Diabetic Neuropathy

Solomon Tesfaye, MB ChB, M.D., F.R.C.P. University of Sheffield, Director of Diabetes Research Royal Hallamshire HospitalGlossop Rd., Sheffield S10 2JF, UKsolomon.tesfaye@nhs.netChristopher H. Gibbons, M.D., M.M.Sc. Beth Israel Deaconness Medical center Palmer 111, Boston MA 02215cgibbons@bidmc.harvard.eduRayaz Ahmed Malik, MSc., MBChB, Ph.D.Room C004, Weill Cornell Medicine-QatarPO Box 24144Doha, Qatar ram2045@qatar-med.cornell.edu ​Aristidis Veves, M.D., DSc, MScBeth Israel Deaconess Medical Center          One Deaconess Road, Palmer 321ABoston, MA 02215aveves@bidmc.harvard.edu

• Section 1: Clinical Features and Diagnosis.- Chapter 1. Introduction.- Chapter 2. The Epidemiology of Diabetic Neuropathy.- Chapter 3. Clinical Features Diabetic Neuropathies.- Chapter 4. Neuropathy in Type 1 and Type 2 Diabetes.- Chapter 5. Clinical Diagnosis of Diabetic Peripheral Neuropathy.- Chapter 6. Diagnostic Techniques for Diabetic Peripheral Neuropathy.- Chapter 7. Sensory Profiles and Diabetic Neuropathy.- Chapter 8. Growth Factors and DPN.- Chapter 9. Treatment Induced Neuropathy of Diabetes (TIND).- Chapter 10. Focal and Multifocal Neuropathies.- Chapter 11. Diabetes and the motor unit.- Chapter 12. Cardiovascular autonomic neuropathy.- Chapter 13. Diabetic Neuropathy and Quality of Life.- Section 2: Pathophysiology.- Chapter 14. Genomics of diabetic neuropathy.- Chapter 15. Metabolic Mechanisms in Diabetic Neuropathy.- Chapter 16. Dyslipidaemia, Bioenergetic and InflammtoryMechanisms of Nerve Injury in Diabetes.- Chapter 17. Neuronal and Schwann Cell Death in Diabetic Neuropathy.- Chapter 18. Diabetes and the Sensory Neuron.- Chapter 19. Spinal cord structure and function.- Chapter 20. Diabetes  Encephalopathy.- Chapter 21. Lifestyle and dietary modifications:  relevance in the management of diabetic neuropathy?.- Chapter 22. Pathophysiology of neuropathic pain.- Chapter 23. Central Nervous System involvement in Diabetic Neuropathy.- Section 3: Clinical consequences and Treatments.- Chapter 24. Treatment of Painful Diabetic Neuropath.- Chapter 25. Disease modifying treatments for Diabetic Peripheral Neuropathy.- Chapter 26. Postural hypotension and Sudomotor dysfunction.- Chapter 27. Gastrointestinal Neuropathy.- Chapter 28. Genitourinary Neuropathy.