Natural Secondary Metabolites

Márcio Carocho is a researcher at the Centro de Investigação de Montanha (CIMO) of the Instituto Politécnico de Bragança, in Portugal. His main research topics focus on chemistry of natural products, new foods, food additives and bio-based food coatings. Marcio Carocho has a European PhD degree in Pharmacy from the Complutense University of Madrid, a master and bachelor’s degree in biotechnology from the Instituto Politécnico de Bragança. He has been awarded a post-doc research grant the by Portuguese government and more recently a national research contract. He has published over 50 research articles and 10 book chapters, and is an author of several patents, over the 10 years of he’s career. He has supervised several master and PhD students. Sandrina Alves Heleno is a Researcher at the Mountain Research Centre of the Polytechnic Institute of Bragança, Portugal. She completed her PhD in Sciences, specialty in Chemistry in 2014 at the University of Minho, the Master in biotechnology in 2010 and the Degree in Biotechnology Engineering in 2008 at the Polytechnic Institute of Bragança. After her PhD, she was awarded with a Postdoctoral grant until 2019, in the same year that she was awarded with a Researcher Contract. She has a very significant research activity, that resulted in dozens of scientific publications in high impact factor journals, several international and national patents, and in the participation as a Principal Investigator of several financed projects. Her research was already been distinguished by the award of different prizes, including European ones related with the development of natural preserving agents. She also motivates new talents and supervises several graduation, master, PhD students as also Post-Doctoral and researcher fellows.Her main research interests are in the area of Food Science and Technology with an emphasis on the development of sustainable natural additives.Lillian Barros is an assistant researcher at the Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança and vice-coordinator of CIMO and vice-director of the Associate Laboratory SusTEC. She obtained her degree in Biotechnology Engineering (2002) at the Institute Polytechnic of Bragança and obtained her PhD “Doctor Europeus” in Pharmacy (Nutrition and Bromatology) at the University of Salamanca (2008). She has published more than 600 indexed papers, within the highest impact factor journals in Food Science and Technology area and has a 69 h‐index. She has edited several books and book chapters, registered national and international patents, and is principal researcher of several national and international projects. Her scientific work has raised interest and has led to the supervision of several post-doc, PhD and master students. She has received awards from several different organizations. L.B scientific production has been veryrelevant and has reached top positions in the world rankings (Highly Cited Researcher in Clarivate since 2016). Her research targets are mainly in the identification, separation, and recovery of functional molecules from different natural products.

• Part I. History of Secondary Metabolites.- History of Secondary Metabolites: From Ancient Myths to Modern Scientific Validation.- Part II. Plant Secondary Metabolites.- Biochemistry of Secondary Metabolism in Plants.- Phenolic Acids and Derivatives: Description, Sources, Properties and Applications.- Flavonoids.- Terpenes.- Plant Alkaloids: Production, Extraction, and Potential Therapeutic Properties.- Polyketides.- Plant Tocopherols and Phytosterols and Their Bioactive Properties.- Anthra-, Benzo- and Naphthoquinones.- Non-Alkaloid Nitrogen Containing Compounds.- Sulfur Containing Compounds from Plants.- Influence of Genetics on the Secondary Metabolites of Plants.- Part III. Fungi Secondary Metabolites.- Biochemistry of Secondary Metabolism of Fungi.- Phenolic Acids From Fungi.- Terpenes from Fungi.- Alkaloids from Fungi.- Polyketides from Fungi.- Fungal Quinones: Benzo-, Naphtho- and Anthraquinones.- Non-Alkaloid Nitrogen Containing Compounds from Fungi.- Sulfur Containing Compounds from Fungi.- Mycosterols.- Influence of Genetics on the Secondary Metabolism of Fungi.- Part IV. Food Industry.- Applications of Plant Secondary Metabolites in the Food Industry.- Applications of Fungi Secondary Metabolites in the Food Industry.- Part V. Pharmaceutical Industry.- New Trends from Plant Secondary Metabolism in the Pharmaceutical Industry.- New Trends from Fungi Secondary Metabolism in the Pharmaceutical Industry.- Part VI. Other Industries.- Cosmetic Industry: Natural Secondary Metabolites for Beauty and Aging.- Biodyes: A Sustainable Approach for Textile Dyeing.- Part VII. Future of Secondary Metabolites.- New Challenges and Opportunities from Secondary Metabolites.