This book constitutes the refereed post-conference proceedings of the 8th EAI International Conference on Nature of Computation and Communication, ICTCC 2022, held in Vinh Long, Vietnam, in October 27-28 2022.The 11 revised full papers presented were carefully selected from 32 submissions. The papers of ICTCC 2022 cover formal methods for self-adaptive systems and discuss natural approaches and techniques for natural computing systems and their applications.