This handbook is an authoritative reference on the Dynamic Data Driven Applications Systems paradigm, pioneered by Dr. Darema, and contains DDDAS-based work conducted by contributing co-authors in numerous areas, to benefit science and technology researchers and practitioners developing DDDAS-based technologies.Beginning with general concepts and history of the DDDAS paradigm in the introductory chapter, this Third Volume in the series contains 33 chapters contributed by leading experts and is organized in nine thematic areas, spanning natural, engineered, or societal systems to enable an accurate understanding, analysis, and control of corresponding complex systems. The thematic areas cover fundamental and foundational methods; materials, structural, and energy systems; healthcare and situation awareness systems; air and space, communications, and cyber systems. The work presented shows how DDDAS unifies the computational and instrumentation aspects of an application system, extends computing notions to span from the high-end to the edge computing and real-time data acquisition and control, adaptively manages the operation of complex, distributed, multimodal systems through high-dimensional, systems-cognizant model-coordination and multi-objective optimization of resources and service delivery; supports methodologies for achieving autonomic and enhanced AI capabilities; DDDAS is foundational concept for Predictive Digital Twins and Dynamic Digital Twins. The authorsexplain how DDDAS unifies the computational and instrumentation aspects of an application system, extends the notion of Smart Computing to span from the high-end to the real-time data acquisition and control, and manages Big Data exploitation with high-dimensional model coordination.
