Dr. Kostas Pantopoulos, PhD., is a Professor of Experimental Medicine at McGill University and Senior Investigator at the Lady Davis Institute of the Jewish General Hospital (1999 – Present). Dr. Pantopoulos earned his PhD in Biochemistry at the Aristotle University (Greece). He had his post-doctoral training with M. W. Hentze at the European Molecular Biology Laboratory (EMBL) in Germany. Dr. Pantopoulos is an internationally recognized scientist in the field of iron metabolism. Research in his laboratory is focusing on regulation of iron metabolism at the cellular and systemic level. Dr. Pantopoulos' laboratory has been continuously supported by extramural funds from the Canadian Institutes for Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC), the Fonds de la recherche en santé du Quebéc (FRSQ), the Cancer Research Society, the Canadian Liver Foundation, and other agencies. Dr. Pantopoulos has received prestigious career awards from CIHR and FRQS and is currently treasurer of the BioIron International Society for the Study of Iron in Biology and Medicine. He is serving in reviewing panels of CIHR and the European Commission and has been ad hoc reviewer for funding agencies in several countries. He is serving in the editorial board of Blood Red Cells & Iron, HemaSphere, Antioxidants, PLoS One, Frontiers in Pharmacology and Frontiers in Hematology. He has previously edited the book “Principles of Free Radical Biomedicine” (2012) Volumes 1-3 (eds Pantopoulos, K. and Schipper, H. M.), Nova Science Publishers, New York, NY.

• Chapter 1. BioIron: Origin, Chemical Properties and Biological Functions.- Chapter 2. Cellular Iron Homeostasis.- Chapter 3. Systemic Iron Metabolism.- Chapter 4. The Labile Side of Iron in Health and Disease: a Narrative Review.- Chapter 5. Iron and Cell Death.- Chapter 6. Dietary Iron Absorption: Biochemical and Nutritional Aspects.- Chapter 7. Hepcidin and Tissue-Specific Iron Regulatory Networks.- Chapter 8. Control of Systemic Iron Homeostasis – Insights Gained from Studying Mouse Models.- Chapter 9. Diagnosis and Treatment of HFEC282Y-Linked Hemochromatosis.- Chapter 10. Diagnosis and Management of Non-HFE Hemochromatosis, Ferroportin Disease and Rare Hereditary Iron Loading Disorders.- Chapter 11. Iron-Loading Anemias.- Chapter 12. Iron Deficiency Anemia.- Chapter 13. Anemia of Inflammation.- Chapter 14. Iron, Hepcidin, and Immunity.- Chapter 15. Iron Metabolism in Cardiovascular Disease.- Chapter 16. Iron and Liver Disease.- Chapter 17. The Impact of Iron Homeostasis in Insulin-Sensitive Tissues and Gut Microbiome on Obesity-Driven Metabolic Disorders.- Chapter 18. Iron and Cancer.- Chapter 19. Neurodegeneration with Brain Iron Accumulation.- Chapter 20. Iron and Bone Pathophysiology.- Chapter 21. Iron and Pregnancy.- Chapter 22. Iron and the Intestinal Microbiome.- Chapter 23. Iron Chelation Therapy.- Chapter 24. Oral and Intravenous Iron Therapy.- Chapter 25. Diagnostics: Markers of Body Iron Status.- Chapter 26. Current Landscape of Hepcidin Therapeutics.

Dr. Kostas Pantopoulos, PhD., is a Professor of Experimental Medicine at McGill University and Senior Investigator at the Lady Davis Institute of the Jewish General Hospital (1999 – Present). Dr. Pantopoulos earned his PhD in Biochemistry at the Aristotle University (Greece). He had his post-doctoral training with M. W. Hentze at the European Molecular Biology Laboratory (EMBL) in Germany. Dr. Pantopoulos is an internationally recognized scientist in the field of iron metabolism. Research in his laboratory is focusing on regulation of iron metabolism at the cellular and systemic level. Dr. Pantopoulos' laboratory has been continuously supported by extramural funds from the Canadian Institutes for Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC), the Fonds de la recherche en santé du Quebéc (FRSQ), the Cancer Research Society, the Canadian Liver Foundation, and other agencies. Dr. Pantopoulos has received prestigious career awards from CIHR and FRQS and is currently treasurer of the BioIron International Society for the Study of Iron in Biology and Medicine. He is serving in reviewing panels of CIHR and the European Commission and has been ad hoc reviewer for funding agencies in several countries. He is serving in the editorial board of Blood Red Cells & Iron, HemaSphere, Antioxidants, PLoS One, Frontiers in Pharmacology and Frontiers in Hematology. He has previously edited the book “Principles of Free Radical Biomedicine” (2012) Volumes 1-3 (eds Pantopoulos, K. and Schipper, H. M.), Nova Science Publishers, New York, NY.

• Chapter 1. BioIron: Origin, Chemical Properties and Biological Functions.- Chapter 2. Cellular Iron Homeostasis.- Chapter 3. Systemic Iron Metabolism.- Chapter 4. The Labile Side of Iron in Health and Disease: a Narrative Review.- Chapter 5. Iron and Cell Death.- Chapter 6. Dietary Iron Absorption: Biochemical and Nutritional Aspects.- Chapter 7. Hepcidin and Tissue-Specific Iron Regulatory Networks.- Chapter 8. Control of Systemic Iron Homeostasis – Insights Gained from Studying Mouse Models.- Chapter 9. Diagnosis and Treatment of HFEC282Y-Linked Hemochromatosis.- Chapter 10. Diagnosis and Management of Non-HFE Hemochromatosis, Ferroportin Disease and Rare Hereditary Iron Loading Disorders.- Chapter 11. Iron-Loading Anemias.- Chapter 12. Iron Deficiency Anemia.- Chapter 13. Anemia of Inflammation.- Chapter 14. Iron, Hepcidin, and Immunity.- Chapter 15. Iron Metabolism in Cardiovascular Disease.- Chapter 16. Iron and Liver Disease.- Chapter 17. The Impact of Iron Homeostasis in Insulin-Sensitive Tissues and Gut Microbiome on Obesity-Driven Metabolic Disorders.- Chapter 18. Iron and Cancer.- Chapter 19. Neurodegeneration with Brain Iron Accumulation.- Chapter 20. Iron and Bone Pathophysiology.- Chapter 21. Iron and Pregnancy.- Chapter 22. Iron and the Intestinal Microbiome.- Chapter 23. Iron Chelation Therapy.- Chapter 24. Oral and Intravenous Iron Therapy.- Chapter 25. Diagnostics: Markers of Body Iron Status.- Chapter 26. Current Landscape of Hepcidin Therapeutics.

Dr. Kostas Pantopoulos, PhD., is a Professor of Experimental Medicine at McGill University and Senior Investigator at the Lady Davis Institute of the Jewish General Hospital (1999 – Present). Dr. Pantopoulos earned his PhD in Biochemistry at the Aristotle University (Greece). He had his post-doctoral training with M. W. Hentze at the European Molecular Biology Laboratory (EMBL) in Germany. Dr. Pantopoulos is an internationally recognized scientist in the field of iron metabolism. Research in his laboratory is focusing on regulation of iron metabolism at the cellular and systemic level. Dr. Pantopoulos' laboratory has been continuously supported by extramural funds from the Canadian Institutes for Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC), the Fonds de la recherche en santé du Quebéc (FRSQ), the Cancer Research Society, the Canadian Liver Foundation, and other agencies. Dr. Pantopoulos has received prestigious career awards from CIHR and FRQS and is currently treasurer of the BioIron International Society for the Study of Iron in Biology and Medicine. He is serving in reviewing panels of CIHR and the European Commission and has been ad hoc reviewer for funding agencies in several countries. He is serving in the editorial board of Blood Red Cells & Iron, HemaSphere, Antioxidants, PLoS One, Frontiers in Pharmacology and Frontiers in Hematology. He has previously edited the book “Principles of Free Radical Biomedicine” (2012) Volumes 1-3 (eds Pantopoulos, K. and Schipper, H. M.), Nova Science Publishers, New York, NY.

• Chapter 1. BioIron: Origin, Chemical Properties and Biological Functions.- Chapter 2. Cellular Iron Homeostasis.- Chapter 3. Systemic Iron Metabolism.- Chapter 4. The Labile Side of Iron in Health and Disease: a Narrative Review.- Chapter 5. Iron and Cell Death.- Chapter 6. Dietary Iron Absorption: Biochemical and Nutritional Aspects.- Chapter 7. Hepcidin and Tissue-Specific Iron Regulatory Networks.- Chapter 8. Control of Systemic Iron Homeostasis – Insights Gained from Studying Mouse Models.- Chapter 9. Diagnosis and Treatment of HFEC282Y-Linked Hemochromatosis.- Chapter 10. Diagnosis and Management of Non-HFE Hemochromatosis, Ferroportin Disease and Rare Hereditary Iron Loading Disorders.- Chapter 11. Iron-Loading Anemias.- Chapter 12. Iron Deficiency Anemia.- Chapter 13. Anemia of Inflammation.- Chapter 14. Iron, Hepcidin, and Immunity.- Chapter 15. Iron Metabolism in Cardiovascular Disease.- Chapter 16. Iron and Liver Disease.- Chapter 17. The Impact of Iron Homeostasis in Insulin-Sensitive Tissues and Gut Microbiome on Obesity-Driven Metabolic Disorders.- Chapter 18. Iron and Cancer.- Chapter 19. Neurodegeneration with Brain Iron Accumulation.- Chapter 20. Iron and Bone Pathophysiology.- Chapter 21. Iron and Pregnancy.- Chapter 22. Iron and the Intestinal Microbiome.- Chapter 23. Iron Chelation Therapy.- Chapter 24. Oral and Intravenous Iron Therapy.- Chapter 25. Diagnostics: Markers of Body Iron Status.- Chapter 26. Current Landscape of Hepcidin Therapeutics.