Handbook of Nutraceuticals

Mrs. R. Rajakumari conducted her doctoral research on Dietary Supplements and Nutraceutical Formulations at Mahatma Gandhi University, Kottayam, Kerala, under the guidance of Dr. Nandakumar Kalarikkal and co-guidance of Professor Sabu Thomas. She was awarded the DST-Inspire fellowship for her PhD studies and has previously been recognized with academic honors during her pharmacy education. She has professional experience in pharmaceutical formulation research and development, with hands-on expertise in analytical instrumentation and industrial processes. Her research interests include nutraceutical formulations, nanotechnology, and pharmaceutical sciences. Professor Sabu Thomas is Vice Chancellor of Mahatma Gandhi University, Kottayam, and Professor of Polymer Science and Engineering at the School of Chemical Sciences. He is also the Founder Director of the International and Inter University Centre for Nanoscience and Nanotechnology. Internationally recognized for his pioneering work in nanoscience, polymer nanocomposites, and green materials, he has contributed to a wide range of applications in the biomedical, automotive, and aerospace sectors. He has received numerous accolades for his research leadership and continues to collaborate with institutions and industry partners around the world.

• Part I: Nutraceuticals and nano nutraceuticals -Formulation and Characterisation.- Nutraceuticals and nano nutraceuticals-overview of the market.- Potential nutraceutical ingredients.- Nutrient Requirements in health and disease. Nutraceutical and nano nutraceuticals for different class of diseases: CNS and Alzheimer’s disease. Nutraceuticals and nano nutraceuticals formulations for CVS and BP.- Nutraceuticals and nano nutraceuticals formulations for obesity, diabetes and kidney disease. Nutraceuticals and nano nutraceuticals formulations for rheumatoid and osteoarthritis. Nutraceuticals and nano nutraceuticals formulations for gastrointestinal disorders. Nutraceuticals and nano nutraceuticals formulations for chronic disease-cancer.- Nutraceuticals and nano nutraceuticals formulations for inflammation and wound healing. Solutions, aqueous solutions, juices and syrups and its evaluation.- Emulsions, Suspensions and evaluation of nutraceuticals and nano nutraceuticals formulations.- Solid dosage forms  and evaluation of nutraceuticals and nano nutraceuticals formulations.- Microscopical methods for evaluating the nutraceuticals and nano nutraceuticals formulations.- Spectroscopical methods for evaluating the nutraceuticals and nano nutraceuticals formulations.- Chromatographic techniques for evaluating the nutraceuticals and nano nutraceuticals formulations.- Microbiological evaluation of the nutraceuticals and nano nutraceuticals formulations.- Stability and thermal analysis for evaluating the nutraceuticals and nano nutraceuticals formulations.- Part II: Controlled and Sustained Delivery of Nutraceuticals and Nano Nutraceuticals.- General overview of controlled and sustained release systems – Its release mechanism and kinetics.- Food derived biopolymers for delivery of nutrients.- Biodegradable synthetic polymers for delivery of nutrients.- Lipid, Self-assembly of lipid particles  and Liposomes delivery of nutritional components.- Micro emulsion, nano emulsion and Emulsion droplet system for delivering bioactive component.- Hydrogels and Organogels for delivering bioactive component.- Nanoencapsulation of controlled release of active components.- Fluidized bed drying, freeze drying and pan coating process of bioactive ingredient.- Spray drying, Spray chilling and spray cooling of nutraceutical ingredient.- Hot melt extrusion and complex coacervation system for delivering bioactive component.- Ionotropic gelation and polyelectrolyte complexation technique for delivering active components.- Interfacial and in-situ polymerization system for delivering bioactives.- Sol-gel, phase inversion precipitation and microfluidic system for controlled delivery of bioactives.- Granulation, electrodynamic atomization and supercritical fluid technology for delivering bioactive components.- Electrospinning technology for controlled delivery of bioactive ingredient.- Assessing the bioavailability and testing the effectiveness of nutraceuticals and nano nutraceuticals.- Future outlook of controlled release delivery technologies for nutraceuticals and nano nutraceuticals.