This book constitutes the proceedings of the International Congress of Computer Science, CORE 2025, Mexico City, Mexico, during October 2025.The 23 full papers included in this book were carefully reviewed and selected from 61 submissions. The CORE 2025 Congress continues a 24-year tradition of bringing together the research community of the Centro de Investigación en Computación (CIC) to discuss cutting-edge developments in computing. This edition focuses on sustainability, highlighting how computational sciences, including Artificial Intelligence (AI) contribute to environmental protection and sustainable development. The congress serves as a platform for showcasing technological advancements, innovative research, and interdisciplinary collaborations that drive sustainable solutions and address global challenges. By addressing both technological progress and social inclusion, CORE 2025 aims to inspire new research directions, foster a collaborative environment, and promote long-term, impactful change for tackling global sustainability challenges through computing.