Regenerative Medicine - from Protocol to Patient

1. Biology of Tissue Regeneration

Inbunden, Engelska, 2016

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Beskrivning

Regenerative medicine is the main field ofgroundbreaking medical development and therapy using knowledge from developmental andstem cell biology, as well as advancedmolecular and cellular techniques. This collection of volumes on Regenerative Medicine: FromProtocol to Patient, aims to explain the scientific knowledge and emergingtechnology, as well as theclinical application in different organ systems and diseases. Internationalleading experts from all over the world describe the latest scientific andclinical knowledge of the field of regenerative medicine. The process of translatingscience of laboratory protocols into therapies is explained in sections onregulatory,ethical and industrial issues. This collection is organized into five volumes: (1) Biology ofTissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering,Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) RegenerativeTherapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientificbasis, therapeutical protocols, clinical translation and practiced therapies in regenerativemedicine.Volume 1 contains eleven chapters addressing the latest basic science knowledge on the “Biologyof Tissue Regeneration”. The principles of cell regeneration control by extracellularmatrix and the biology of stemcell niches are explained. Depicted are the principles ofmolecular mechanisms controlling asymmetric cell division, stem cell differentiation,developmental and regenerative biology, epigenetic and genetic control as well asmathematical modelling for cell fate prediction. Regenerative biology of stem cells in the central nervous and cardiovascular systems leading to complex tissueregeneration in the model species axolotl and zebrafish, as well as the impact of immune signalling on nuclear reprogramming areoutlined. These up to date accounts gives the readers advanced insights into thebiological principles of the regenerative processes in stem cells, tissues andorganisms.

Produktinformation

Utgivningsdatum:2016-05-09
Mått:155 x 235 x 26 mm
Vikt:817 g
Format:Inbunden
Språk:Engelska
Antal sidor:373
Upplaga:3
Förlag:Springer International Publishing AG
ISBN:9783319275819

Utforska kategorier

Cellbiologi inom Naturvetenskap och teknik
Anatomi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin

Mer om författaren

Gustav Steinhoff initiated and leads the Reference and TranslationCenter for Cardiac Stem Cell Therapy (RTC) of the University Medical CenterRostock. He isknown as an expert in the medical field of stem cell therapies and the firstclinician to treat patients with intramyocardial transplantation of purifiedstem cells and is one of the pioneers of these new therapies. Besides hismedical study at the Erasmus University Rotterdam, Gustav Steinhoff performedresearch at the Baylor College in Houston, Texas. He has worked as a surgeon atthe University of Kiel and the Medical School Hannover, where he was appointedas an Associate Professor of Cardiothoracic Surgery in 1998. In 2000 hemoved to the University of Rostock as a Director and Chairman of the Departmentof Cardiac Surgery where he continued his research on cardiac stem celltherapies and tissue engineering.

Innehållsförteckning

1 Extracellular matrix and tissue regeneration, Zygmunt Mackiewicz, Yrjö Tapio Konttinen, Emilia Kaivosoja, Vasily Stegajev, Hanoch Daniel Wagner, Jaakko Levón and Veli-Matti Tiainen.- 2 Stem cell niche, Chenhui Wang, Jun Chen, Pei Wen, Pei Sun and Rongwen Xi.- 3 Stem cells and asymmetric cell division, Rita Sousa-Nunes and Frank Hirth.- 4 Stem cells in the developing and adult nervous system, Fumitaka Osakada and Masayo Takahashi.- 5 Epigenetic mechanisms regulating the transition from embryonic stem cells towards a differentiated neural progeny, Marijn Schouten, Nik Papaloukas, Pascal Bielefeld, Silvina A. Fratantoni and Carlos P. Fitzsimons.- 6 Mathematical models in stem cell differentiation and fate predictability, Wayne M. Eby and Natalia Coleman.- 7 Organ and appendage regeneration in the axolotl, Johanna E Farkas, Piril Erler, Polina D Freitas, Alexandra Sweeney, and James R Monaghan.- 8 Development and regeneration of the vertebrate brain, Brian Key.- 9 Role of innate immune signaling in nuclear reprogramming, Shu Meng, Palas Chandaand John P. Cooke.- 10 Cardiac regeneration in zebrafish, Chi-Chung Wu and Gilbert Weidinger.- 11 Genetics and regeneration in vertebrates, Elizabeth Denise Hutchins and Kenro Kusumi.- Index.