Acute Lung Injury and Repair

Scientific Fundamentals and Methods

AvLynn M. Schnapp,Carol Feghali-Bostwick

Inbunden, Engelska, 2016

Del i serien Respiratory Medicine

550 kr

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Beskrivning

Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.

Produktinformation

Utgivningsdatum:2016-11-14
Mått:155 x 235 x 17 mm
Vikt:465 g
Format:Inbunden
Språk:Engelska
Serie:Respiratory Medicine
Antal sidor:185
Förlag:Springer International Publishing AG
ISBN:9783319465258

Utforska kategorier

Olycksfalls- och akutmedicin inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin
Lungmedicin inom Medicin

Mer om författaren

Lynn M. Schnapp, MDPulmonary, Critical Care, Allergy and Sleep MedicineMedical University of South CarolinaCharleston, SC, USA Carol Feghali-Bostwick, PhDRheumatology and ImmunologyMedical University of South CarolinaCharleston, SC, USA

Recensioner i media

"Basic scientists and clinician investigators with an interest in ARDS are an appropriate audience for this work, which features contributions from clinicians and basic scientists in pulmonary and critical care from academic institutions ... . This is an excellent introduction to work in an area of great interest to intensivists. Investigators needing to understand approaches to an important clinical problem and clinicians needing a better understanding of relevant experimental methods will enjoy and benefit from this book." (David J. Dries, Doody's Book Reviews, January, 2017)

Innehållsförteckning

Methods to Study Lung Injury and Repair.- Mouse Models of Acute Lung Injury.- Transgenic Animal Models in Lung Research.- Fundamental Methods for Analysis of Acute Lung Injury in Mice.- Invasive Measurement of Pulmonary Function in Mice.- Analysis of Epithelial Injury and Repair.- Flow Cytometric Evaluation of Acute Lung Injury and Repair.- Lung Imaging in Animal Models.- Genetic and Genomic Approaches to Acute Lung Injury.- MicroRNA Analysis in Acute Lung Injury.

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