This book constitutes the refereed proceedings of the 15th International Conference on Mobile Web and Intelligent Information Systems, MobiWIS 2018, held in Barcelona, Spain, in August 2018.The 15 full papers together with 2 short papers presented in this volume were carefully reviewed and selected from 50 submissions. The papers of the MobiWIS 2018 deal with areas such as: mobile web and apps, wireless sensor networks, web services, cloud services, web applications, and various web technologies.